2016年6月29日星期三
Chloroquine for sale
Product Name: Chloroquine
CAS: 54-05-7
Molecular formula: C18H26ClN3
Molecular Weight: 319.87
Product Description: This product and other 4 - aminoquinoline antimalarial drugs (such piperaquine, sinensis acetaminophen, etc.) mainly work on parasites in the red period was likely to interfere with the colonization of the parasite replication plan of DNA and transcription or Off they operate during swallowing, so that the body of the insect death because of a lack of amino acids. This product can effectively control the symptoms of malaria attacks. For infrared period without effect, to avoid repetition, but also because of the role is preserved, time to recurrence (p. Falciparum, because there was no time to infrared so it can be healing ). For primary infrared period is invalid, no direct effect on gametophyte is, consequently, can not make the prevention of etiology, can interrupt transmission. At present, there are a number of Plasmodium falciparum found this clinical resistance, reduce the effectiveness of the product, so that in many cases, other combinations of anti-malarial drug or drugs must change. This product is rapidly and completely absorbed after oral and intestinal absorption, only 8% of feces. 1 to 2 hours after the maximum blood drug concentration namely T1 / 2 to 48 hours. May in the fabric are stored internal organs, can red.
Etnynodiol Diacetate
This review of the monograph ethynodiol diacetate (ED) include structural and molecular formulas molecular weight ED physical properties (melting point, optical rotation, and solubility) physical data (synonyms and trade names) and chemical and chemical and manufacture, use, appearance and analysis of ED. ED production is done by reducing ethindrone to ethynodiol which then product with acetic anhydride in pyridine the acetylated ED. ED is of course not known to occur. Applications in human medicine are similar to those of progesterone; It is mainly used in oral contraceptive, in combination with an estrogen and also used dysfunctional uterine bleeding, amenorrhea, and for the treatment of endometriosis; the French have to treat ED to treat advanced breast cancer. Analytical method for determining the ED than bulk chemicals are tabulated. The relevant biological data for the evaluation of carcinogenic risk to humans will be presented shortly. In laboratory experiments, ED has been tested in mice, rats and monkeys alone or in combination with an estrogen. ED product of mammary tumors in male mice castrated male rats. When combined with an estrogen, increases the incidence of pituitary tumors in mice, and malignant breast tumors in rats of both sexes. ED must be reported embryolethal for embryos before and postimiplantation and in some species have teratogenic effects. No human data are available, with the exception of studies on the COC, the side effects which may be attributed ED implicitly. Therefore, there is limited evidence of carcinogenicity of erectile dysfunction in animals and ED may be associated with an increased incidence of benign liver adenoma and decrease the incidence of benign breast disease associated with oral contraceptives with formulations together combined.
Carbetocin
Product Name: Carbetocin
CAS: 37025-55-1
Molecular formula: C45H69N11O12S
Molecular Weight: 88.16
Product Description: Used for selective cesarean epidural or lumbar hemp after surgery to prevent uterine contractions and bleeding postpartum. For emergency section, a classical caesarean another epidural anesthesia or spinal anesthesia in cesarean section or maternal history of heart apparent disease, hypertension, disease known coagulation or liver, kidneys and endocrine diseases (not including gestational diabetes) card when using oxytocin has not been studied, after vaginal delivery does not map to the treatment of oxytocin for the appropriate research, the dose is in the air.
Treatment with indinavir
In this double-blind study, 97 patients who had received treatment zidovudine for at least six months with HIV, and 50 to 400 CD4 cells per cubic millimeter, and at least 20,000 HIV RNA copies per milliliter had a randomly were assigned to three treatments for 52 weeks: 800 mg indinavir every eight hours; 200 mg zidovudine 150 mg every eight hours with lamivudine twice daily in combination; or all three drugs. Patients had to monitor the occurrence of adverse events and changes in viral load and CD4 cell count.
RESULTS:
The decrease in HIV RNA during the first 24 weeks were higher in the group of three drugs in other groups (p <0.001 for each comparison). RNA levels dropped to less than 500 copies per milliliter at week 24 in 28 of 31 patients in the group of three drugs (90 percent), 12 of 28 patients in the indinavir group (43 percent), and none of the 30 patients in the zidovudine group -lamivudine. Increasing the number of CD4 cells during the first 24 weeks was higher in the two groups receiving indinavir than in the zidovudine-lamivudine group (P <or = 0.01 for each comparison). Changes in viral load and CD4 count remained until 52 weeks. All doses were generally well tolerated.
CONCLUSION:
In most patients with HIV infection with antiretroviral therapy before, the combination of indinavir, zidovudine, lamivudine, and reduced levels of HIV RNA to less than 500 copies per milliliter for as long as one year.
RESULTS:
The decrease in HIV RNA during the first 24 weeks were higher in the group of three drugs in other groups (p <0.001 for each comparison). RNA levels dropped to less than 500 copies per milliliter at week 24 in 28 of 31 patients in the group of three drugs (90 percent), 12 of 28 patients in the indinavir group (43 percent), and none of the 30 patients in the zidovudine group -lamivudine. Increasing the number of CD4 cells during the first 24 weeks was higher in the two groups receiving indinavir than in the zidovudine-lamivudine group (P <or = 0.01 for each comparison). Changes in viral load and CD4 count remained until 52 weeks. All doses were generally well tolerated.
CONCLUSION:
In most patients with HIV infection with antiretroviral therapy before, the combination of indinavir, zidovudine, lamivudine, and reduced levels of HIV RNA to less than 500 copies per milliliter for as long as one year.
Ketanserin price
Product name: ketanserin
CAS: 74050-98-9
Molecular formula: C22H22FN3O3
Molecular Weight: 395.4268
Product Description: This product is 5 - receptor blockers of serotonin, selective blockade of serotonin 5-HT2, are weaker and H receptor antagonist. Do you have a decrease in blood pressure in patients with peripheral resistance, decreased the apparent renal vascular resistance, normal for the function. With vascular obstructive lesions of blood supply of the lower limbs can improve. For Renault tissue perfusion can improve disease increased blood flow to the skin. After intravenous injection, right atrial pressure, pulmonary artery pressure and pulmonary capillary pressure can reduce stress.
2016年6月27日星期一
What is Fluoxetine
Product Name: fluoxetine
CAS: 54910-89-3
Molecular formula: C17H18F3NO
Molecular Weight: 309.33
Product Description: A kind of serotonin reuptake inhibitors, through synaptic cells of the neurotransmitter serotonin reuptake inhibition to increase levels of serotonin post-synaptic receptors can and extracellular. And for other receptors such as alpha adrenergic, beta adrenergic, serotonin, dopamine can wait, fluoxetine is almost no force.Well link from the gastrointestinal tract after oral consumption, the food will not affect its bioavailability. In combination with the many plasma proteins after absorption, is widespread. The drugs reach plasma concentrations at steady state after a few weeks.
CAS: 54910-89-3
Molecular formula: C17H18F3NO
Molecular Weight: 309.33
Product Description: A kind of serotonin reuptake inhibitors, through synaptic cells of the neurotransmitter serotonin reuptake inhibition to increase levels of serotonin post-synaptic receptors can and extracellular. And for other receptors such as alpha adrenergic, beta adrenergic, serotonin, dopamine can wait, fluoxetine is almost no force.Well link from the gastrointestinal tract after oral consumption, the food will not affect its bioavailability. In combination with the many plasma proteins after absorption, is widespread. The drugs reach plasma concentrations at steady state after a few weeks.
Indinavir for sale
Product Name: indinavir
CAS: 150378-17-9
Molecular formula: C9H13N3O3
Molecular Weight: 711.88
Product description: indications and in combination with other antiretroviral drugs is used, used in the treatment of adults and children infected with HIV - 1 clinical studies showed adults: the spread of HIV / AIDS to slow down a process or die - to increase serum RNA virus in low - - risk of persistence of overall survival allows higher CD4 cell number is persistence
CAS: 150378-17-9
Molecular formula: C9H13N3O3
Molecular Weight: 711.88
Product description: indications and in combination with other antiretroviral drugs is used, used in the treatment of adults and children infected with HIV - 1 clinical studies showed adults: the spread of HIV / AIDS to slow down a process or die - to increase serum RNA virus in low - - risk of persistence of overall survival allows higher CD4 cell number is persistence
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