Bumetanide

Product name:Bumetanide
CAS: 28395-03-1
Molecular Formula:C17H20N2O5S 
Molecular weight:364.42
Appearance:white powder
Stability:Stable
Shelf life:2 years
Product description :In the brain, bumetanide blocks the NKCC1 cation-chloride co-transporter, and thus decreases internal chloride concentration in neurons. In turn, this concentration change makes the action of GABA more hyperpolarizing, which may be useful for treatment of neonatal seizures, which quite often are not responsive to traditional GABA-targeted treatment, such as barbiturates. Bumetanide is therefore currently under evaluation as a prospective antiepileptic drug.