2016年4月29日星期五

Serpin A3 price


Product Name: A3 SERPIN

Type: Other biological products

Product Description:
, Also known as Serpin A3 α1-antichymotrypsin is a major constituent of associated with Alzheimer's disease plaques. Deficiency A3 serpin activity is associated with chronic obstructive pulmonary disease.

Epithelial membrane antigen

Product Name: epithelial membrane antigen

Symbols: EMA

Type: antibody antigen

Product Description:
The epithelial membrane antigen (EMA) is a group of highly glycosylated transmembrane proteins, 40-425 kDa, based on the high molecular weight glycoproteins of the human milk fat globule (HMFG). EMA is found in a variety of glandular (secretory) epithelium such as breast, eccrine and apocrine glands and the pancreas whereas little or no EMA is in the gastrointestinal epithelium, the epithelium expressed and endocervical glands prostate.

Kallikrein 10 for sale


Product name: kallikrein 10

Type: Other biological products

Product Description:
The family of the gene for human tissue kallikrein (KLK) has 15 members, who play an important role in cancer.
Kallikrein 10 a secreted serine protease is brought into the growth and recent outbreak of several human tumors.

Buy RELM alpha


Product Name: RELM alpha

Type: Other biological products

Product Description:
RELM alpha, found in inflammatory zone belongs to known RELM1 / FIZZ family cysteine rich secretory proteins and homology resistin. It is abundantly expressed in white adipose tissue, but not in preadipocytes, but the 3T3-L1 adipocytes. RELM alpha expression is detected in the bronchial epithelium and type II pneumocytes. RELM beta is a cysteine-rich protein is specifically expressed in the intestine. It is highly homologous resistin and RELM alpha.

Semaphorins price

Product Name: semaphorins

Type: Other biological products

Product Description:
The shape of semaphorin yet described most axon guidance family indexes upwardly. Semaphorin (classes 3-7 in vertebrates) are divided into 8 classes.
Semaphorin were rollers shown in cardiovascular development and regulation of immune cells have antigen presentation.

2016年4月28日星期四

VLDL Receptor

Product Name: VLDL Receptor

Type: Other biological products

Product Description:
The gene encoding the receptor VLDL is highly expressed in heart, muscle and adipose tissue, which are active in the metabolism of fatty acids; virtually no expression in the liver. VLDL appears to play a crucial role in the metabolism of triglycerides.

Adrenal antibodies


Product name: adrenal antibodies

Type: antibody antigen

Product Description:
The adrenal term antibody refers to a variety of auto-antibodies which are directed against the adrenal cortex, surrounds the outer fabric layer of each of the adrenal glands. adrenal antibodies are known as adrenocorticol antibodies or, more precisely, adrenocorticol autoantibodies (ACA) known. ACA destroy adrenal tissue, disrupting the production of hormones, adrenal damage by various proteins, particularly the 21-hydroxy-enzymes.

Midkine price


Product name:Midkine(MK)

Type:
Other Biological Products

Product description:
Midkine (MK) is the first cloned gene in a new family of heparin- binding growth/differentiation factors involved in the regulation of growth and differentiation.

Buy beta-NGF


Product name: beta-NGF

Model: 100 UG

Type: Other biological products

Product Description:
beta-NGF acts as a neurotrophic factor through its receptor (beta-NGFR) and is involved in the development and maintenance of sensory and sympathetic nervous system. NGF-beta also involved in the growth and differentiation of B cells and the survival of B cells

Buy Flibanserin


Product Name: flibanserin

CAS: 167933-07-5

Molecular formula: C20H21F3N4O

Molecular Weight: 390.4g / mol

Description:. Flibanserin has preferential affinity for serotonin 5-HT (1A), dopamine D (4k) and serotonin 5-HT (2A) receptors.It currently the drug is considered for women with decreased sexual desire [2 ] is a 5-HT1A receptor agonist serotonin, a serotonin 5-HT2A receptor antagonist and a partial agonist at the dopamine D4 receptor, which was initially developed as an antidepressant.

Lactobacillus fermentum for sale


Product name: Lactobacillus fermentum
Description: Lactobacillus fermentum is a species of Gram-positive bacteria of the genus Lactobacillus. It is associated with active caries lesions.It also commonly found in the fermentation of plants and animals was found material.It applied sourdough.A some strains are probiotic or "friendly" bacteria in animals and at least one strain was urogenital infections treated women.

Buy Nitrendipine shop


This study compared the efficacy and safety of the 8 weeks of treatment open the dihydropyridine calcium antagonist amlodipine and nitrendipine mild to moderate hypertension. The interim analysis of the data of 74 patients (43 men, 31 women) showed that the normalized diastolic blood pressure amlodipine (less than or equal to 90 mmHg) at 95% of patients compared with 83% of patients treated with nitrendipine. Nitrendipine produced a statistically significant increase in heart rate at 2 and 4 weeks of treatment, but there was no significant change in heart rate in patients treated with amlodipine. Amlodipine in patients less side effects (26%) than the nitrendipine group treated (47%), with two patients in the nitrendipine group treatment discontinuation due to adverse events related to treatment. Adverse events in the amlodipine-treated group were mild to moderate. The incidence of flushing was higher in patients treated with nitrendipine (25%) than in patients treated amlodipine (10%). This difference in the incidence of side effects vasodilators is probably explained by the gradual onset of action with amlodipine.

Buy Creatinol- o-phosphate

Die Wirkung von Creatinol-O-phosphat (N-methyl-N- (beta-hydroxyethyl) guanidin O-phosphat, creatinolfosfate, Aplodan) Vorbehandlung wurde auf die Rückgewinnung von Kontraktilität von Ratten isolierten Herzen nach Hypoxie oder Ischämie untersucht. In Normoxie Kreatinol-O-Phosphat (100 mumol / l) hervorgerufen nur eine positive inotrope Wirkung, wenn die Glucose in der physiologischen Lösung vorhanden war, es evoziert auch einen leicht negativen chronotropen Wirkung, die unabhängig von Glucose war. Wenn Creatinol-O-phosphat bei Hypoxie, in der physiologischen Lösung vorhanden war, wurde die Rückgewinnung der Kontraktion nach Reoxygenierung (in Abwesenheit des Arzneimittels) in einer dosisabhängigen Art und Weise verbessert. Wenn Creatinol-O-phosphat in einer physiologischen Lösung vor der Ischämie vorhanden war, war die Wiederherstellung der Kontraktilität nach Reperfusion höher als bei Kontrollen; das Vorhandensein von Kreatinol-O-Phosphat während der Reperfusion nach Ischämie beschleunigt die Erholung der Kontraktilität. Die Wirkung von Creatinol-O-phosphat auf die Erholung der kardialen Kontraktilität nach der Ischämie wurde auch mit einer Kardioplegie-Lösung in teilweise geschützten Herzen beobachtet. Es wird vorgeschlagen, dass Creatinol-O-phosphat seine kardioprotektive Wirkung durch eine Wirkung auf anaerobe Glykolyse ausüben könnte.

Epirubicin Hydrochloride


Product name: epirubicin hydrochloride
CAS: 56390-09-1
Molecular formula: C27H29NO11.HCl
Molecular Weight: 579.9802
Product Description: The isomers of doxorubicin, the action mechanism of nuclear DNA bases interfere with the transcription process, prevents the formation of mRNA, thus inhibiting the synthesis of DNA and RNA directly incorporated. In addition, adriamycin table topology Ⅱ isomerase inhibitory effect. For the cell cycle of tumor -unspezifischen drug are effective for a variety of portability. Compared to adriamycin curative effect is equal to or slightly greater, but less toxicity to heart.

2016年4月27日星期三

20% n-Butyllithium cyclohexane price


product name: 20% n-butyl lithium cyclohexane

Molecular formula: n-C4H9Li
Property: colorless transparent yellow liquid
Molecular Weight: 64.06
Density: 0.75 g / ml at 20 ° C,
Spontaneous combustion nature: spontaneous combustion

Use: organic catalyst

packaging:
5-10,000 L / tank or by the user.

Transport:
Mail, banning air traffic
Shipping 4.2, UN 2445
Country Shopping 4.2, UN 2445

Note:
Easy to ignite when exposed to produce fuel gas and corrosive dust. Far from preventing water, air, oxidized material, heat and sparks or damage disclosure tank.

Methoxyfenozide


Product Name: Methoxyfenozid

CAS: 161050-58-4

Molecular formula: C22H28N2O3

Molecular Weight: 368.4693

Description: benzoic acid, 3-methoxy-2-methyl-2- (3,5-dimethylbenzoyl) -2- (1,1-dimethylethyl) hydrazide; Methoxyfenozide (BSI, pa ISO, ANSI); rh-2485; N-tert-butyl-N '- (3-methoxy-2-methylbenzoly) -3,5-dimethylbenzohydrazide; runner; N'-tert-butyl-N '- (3,5-dimethylbenzoyl) -3-methoxy-2-methylbenzohydrazide

Hafnium tetrachloride for sale


Product name: Hafnium
CAS: 13499-05-3
Molecular formula: Cl4Hf
Molecular Weight: 320.3g / mol
Description: hafnium (IV) chloride, the inorganic compound having the formula HfCl 4. The colorless solid is the precursor of most hafnium organometallic compounds. It acts as a Lewis acid catalyst for alkylation reactions and specific isomerism.

Gemifloxacin price


Product name: gemifloxacin
CAS: 175463-14-6
Molecular formula: C18H20FN5O4
Formula Weight: 389.39
Description:
Gemifloxacin mesylate (Factive brand Oscient Pharmaceuticals) is a broad-spectrum quinolone antibacterial agent in the oral treatment of acute bacterial exacerbation of chronic bronchitis and mild to moderate pneumonia. Oscient Pharmaceuticals has licensed the drug from LG Life Sciences Korea.

2016年4月26日星期二

Sugar Activated Carbon price


Product name: Sugar activated carbon (SJ-300)

Caramel decolorization (%): ≥120

pH: 3-5

Product Description: Sugar activated carbon (SJ-300) is adapted for bleaching and refining sucrose, maltose, glucose, maltose, ribose, lactose, xylose, starch and sugar other sugars.It is also suitable for citric acid, cystine, sodium glutamate, saccharin, fluorescent, glycerol, vegetable oil, soy sauce, spices, beverages, and food additives industry, with deep cleaning, whitening, cleaning and sophisticated functions.

Human Lens Epithelial Cells


Product Name: HOPC (human oligodendrocytes progenitor cells)

Specifications: 1 x 106 cells, 1 ml

Type: System CNS cell

Product Description:
HOPC be isolated from human brain tissue. HOPC cryopreserved at secondary culture and delivered frozen. HOPC are characterized by the immunofluorescence method with A2B5 and nestin antibodies.

What is Imidapril HCl

Imidapril (imidapril) nephropathy is a long action, non-sulfhydryl converting enzyme (ACE) inhibitor used in the treatment of hypertension, chronic heart failure (CHF), acute myocardial infarction (AMI) has been used clinically, and diabetic. It caused the unique advantage over other ACE inhibitors in a lower incidence of dry cough. After oral administration, the administration imidapril is rapidly converted in the liver to its active metabolite imidapril. Plasma levels of imidapril gradual increase in proportion to the dose and slowly decrease. Time to maximum plasma concentration (T (max)) is 2.0 hours to 9.3 hours and imidapril to reach for imidaprilat. The half-life of elimination (t (1/2)) of imidapril and imidaprilat is 1.7 and 14.8 h, respectively. Imidapril and its metabolites are excreted primarily in the urine. When ACE inhibitors, imidaprilat is as effective as enalapril, an active metabolite of enalapril, and about twice as high as captopril. In hypertensive patients, blood pressure was reduced to 24 hours after administration of imidapril. The antihypertensive effect of imidapril was dose-dependent. The maximum decrease in blood pressure and plasma ACE has been performed with imidapril, 10 mg once daily, and the additive effect was not evident with the higher doses. In patients with an acute myocardial infarction, imidapril improved ventricular ejection fraction and reduces brain natriuretic peptide plasma (BNP). In patients with mild to moderate CHF [New York Heart Association (NYHA) II-III], imidapril increased exercise time and physical work capacity and a decrease in plasma ANP (ANP) and the rate of BNP in a dose-dependent manner. In patients with diabetic nephropathy, imidapril reduces urinary albumin excretion. Interestingly, improving imidapril dysphagia asymptomatic patients with a history of stroke. In the same patient, it increases the serum levels of substance P while the Angiotensin II receptor antagonist, losartan was ineffective. These studies show that imidapril is an inhibitor of ACE versatile. In addition to its effectiveness in the treatment of hypertension, CHF, and AMI imidapril has beneficial effects in the treatment of diabetic nephropathy and asymptomatic dysphagia. Good penetration in tissues and inhibition of tissue ACE by imidapril contribute to its effectiveness in cardiovascular complications of hypertension to prevent. The main advantages of imidapril are its activity in the treatment of various cardiovascular diseases and a lower incidence of cough in comparison with some of the older ACE inhibitors.

What is Obacunone

Overexpression of the enzyme aromatase was CYP19 involved in the development of breast cancer carcinogenesis estrogen dependent. Obacunone, a natural compound that has been found in citrus demonstrated for a variety of biological activities, including anti-cancer and anti-inflammatory. In this study, we obacunone and obacunone glucoside (OG) isolated from lemon seeds, then cut these connections chromatographic techniques and characterized by HPLC, LC-MS and 2D NMR spectral analysis. To examine the anti-cancer mechanism and anti-aromatase limonoids tested their cytotoxic effect on the human breast cancer breast cells (MCF-7) and non-malignant (MCF-12F). MTT assay confirmed that obacunone was strong MCF-7 cell proliferation is inhibited, affecting the breast without non-malignant cells. Treatment with obacunone increased apoptosis by upregulating the expression of pro-apoptotic protein Bax and downregulation of anti-apoptotic Bcl-2 and G1 cell cycle arrest inducing protein. Further obacunone aromatase activity in a significantly inhibited the in vitro enzyme assay. Exposure of MCF-7 breast cancer cells for expression downregulated obacunone of inflammatory molecules, including the nuclear factor kappa B (NFkB) and cyclooxygenase-2 (COX-2). In addition, we found that the activation of p38 mitogen obacunone by activated protein kinase (MAPK) COX-2 and NF? B is inhibited. Finally, the recording level obacunone in MCF-7 cells, as measured by HPLC, and its structure was confirmed by LC-HRMS. This study showed that obacunone have the potential can prevent breast cancer estrogen-sensitive by inhibiting the enzyme aromatase and inflammatory pathways, and activation of apoptosis.

Hydrogenated lecithin shop


Product Name: hydrogenated lecithin
CAS: 92128-87.5
Description: lecithin and hydrogenated lecithin are -verschieden in a variety of cosmetic formulations such as skin conditioning agents and surfactants are used as emulsifiers. Hydrogenated lecithin is not used as the surfactant suspension.

Buy Obacunone


Product Name: obacunone

CAS: 751-03-1

Molecular weight: 454.51g / mol

Molecular formula: C26H30O7

Description: The inhibition induced azoxymethane colon carcinogenesis in male F344 rats by limonoids obacunone of citrus and limonin.It is white and fine powder.Potentiating effect obacunone of Dictamnus dasycarpus cytotoxicity of microtubule inhibitors, vincristine, vinblastine and taxol.

Zidovudine


Product Name: zidovudine
CAS: 30516-87-1
Molecule formula: C10H13N5O5
Formula Weight: 283.24
Description:
Zidovudine (INN) or azidothymidine used (AZT) (also called ZDV) is a nucleoside transcriptase inhibitor analogue reverse (INTI), a type of antiretroviral drugs to treat HIV / AIDS. It is an analog of thymidine.
AZT was the first treatment approved for HIV, under the name Retrovir and sold Retrovis. the use of AZT was a major breakthrough in the treatment of AIDS in the 1990s, which changed significantly during the disease and helped destroy the idea that HIV / AIDS was a death sentence immediate. AZT slowed considerably the spread of HIV, but they do not stop completely. This allows HIV over time become resistant AZT, and for this reason AZT is usually in conjunction with other NRTIs and antiviral drugs. In this form AZT is used as an ingredient in Combivir and Trizivir among others. Zidovudine is included in the "List of essential medicines" World Health Organization, a list of minimum medical needs for a basic health care system.

Naltrexone Hydrochloride shop

Product Name: Naltrexone hydrochloride
Specification: USP 26
CAS no. 16676-29-2
Description:
It is used to treat the effects of opioid analgesics, including heroin, morphine and methadone patients to block the recovery of substance abuse, and to treat addiction to ethanol.

Vinpocetine price


Product Name: Vinpocetine
CAS: 42971-09-5
Molecular formula: C22H26N2O2
Formula Weight: 350.45
Description:
Vinpocetine is reported that improved cerebral blood flow [2] and the neuroprotective effects and is used as a medicine in Europe for the treatment of cerebrovascular disease and memory disorders associated with age.
Vinpocetine is marketed as a supplement for vasodilation and as a nootropic to improve the wide memory. In other words, vinpocetine can support to help by activating brain metabolism brain functions such as concentration and memory. There is anecdotal report unpleasant side effects of vinpocetine in a small subset of users. A lower starting dose is often recommended.
Vinpocetine has been identified as a potent anti-inflammatory agent which may have a potential role in the treatment of Parkinson's disease and Alzheimer's disease.

Buy Etamsylate


Product Name: etamsylate
CAS: 2624-44-4
Molecular formula: C10H17NO5S
Molecular Weight: 263.3107
Product Description: For the prevention and treatment of bleeding before surgery, but for intestinal bleeding, bleeding and urinary tract bleeding, etc.

7-Deazaguanine

Product name:7-Deazaguanine
CAS:7355-55-7
Molecular Formula:C6H6N4O
Molecular Weight:150.14g/mol
Description:7-deazaguanine, guanine analogue, is able to be sequence specifically incorporated into DNA.It is pink solid.Synonyms:4H-Pyrrolo[2,3-d]pyrimidin-4-one, 2-amino-1,7-dihydro- (9CI);2-Amino-3,4-dihydro-4-oxo-7H-pyrrolo[2,3-d]pyrimidine;2-amino-3H-pyrrolo[2,3-d]pyrimidin-4(7H)-one

B-Lupulic acid for sale

Product name:B-Lupulic acid
CAS:468-28-0
Molecular Formula:C26H38O4
Molecular Weight:414.58g/mol
Description:Synonyms: 2,4-cyclohexadien-1-one,3,5-dihydroxy-4-isovaleryl-2,6,6-tris(3-methyl-2-but;3,5-dihydroxy-2,6,6-tris(3-methyl-2-butenyl)-4-(3-methyl-1-oxobutyl)-2,4-cyc;b’’-acid;lohexadien-1-one;lupulon;LUPULONE;B-LUPULIC ACID;BETA-LUPULIC ACID

From:http://www.chemicals-chemicals.net/Intermediates/B-Lupulic-acid/

tert-Butyl glycinate price

Product name:tert-Butyl glycinate
CAS:6456-74-2
Molecular Formula:C6H13NO2
Molecular Weight:131.17g/mol
Description:Boiling point is 29-31°C 2mm.Density is 0,96 g/cm3.Synonyms: GLYCIN-TERT-BUTYL ESTER;GLYCINE T-BUTYL ESTER;GLYCINE TERT-BUTYL ESTER;TERT-BUTYL GLYCINATE;tert-Butyl glycinate~H-Gly-OtBu;Glycinetert-butylester,97%;Glycine, 1,1-dimethylethyl ester;Aminoacetic acid tert-butyl ester

Glycine lauryl ester hydrochloride for sale


CAS:16194-11-9
Molecular Formula:C14H30ClNO2
Molecular Weight:279.85g/mol
Description:Glycine lauryl ester hydrochloride,Glycine lauryl ester hydrochloride,Glycine lauryl ester hydrochloride,Glycine lauryl ester hydrochloride,Glycine lauryl ester hydrochloride,Glycine lauryl ester hydrochloride,Glycine lauryl ester hydrochloride.

Acetylenedicarboxamide

CAS:543-21-5
Molecular Formula:C4H4N2O2
Molecular Weight:112.09g/mol
Description:Acetylenedicarboxamide is cream to beige fine crystalline powder.Melting point is 179 °C.Synonyms: Acetylendicarbonsaeureamid;Acetylenedicarboxylic acid diamide;acetylenedicarboxylicaciddiamide;Aquamycin;Lenamycin;Renamycin 

2016年4月25日星期一

Tiotropium bromide hydrate for sale


Product Name: tiotropium bromide hydrate
CAS: 139404-48-1
Molecular formula: C19H22BrNO 4S2.H2O
Molecular weight: 490.43g / mol
Description:
Synonyms: (1a, 2b, 4b, 5a, 7b) -7 - [(hydroxydi-2-thienylacety l) oxy] -9,9-dimethyl-3-oxa-9-azoniatricyclo [3.3.1.02,4] nonane bromide hydrate; (1a, 2b, 4b, 5a, 7b) -7 - [(hydroxy, di-2-thienyl acetyl) oxy] -9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonanbromide;(1R,2R,4S,5S,7S)-7-[2-HYDROXY-2,2-DI(2-THIENYL)ACETOXY]-9,9-DIMETHYL-3-OXA-9-AZONIATRICYCLO[3.3.1.02,4] NONANE BROMIDE MONOHYDRATE; tiotropium hydrate

What is SW13,and for sale


The cell line of human adrenal carcinoma, SW13, was reported both BRG1 and BRM deficient expression and therefore lacks a SWI / SNF complex functional. We found that the original is composed of SW13 cell line two subtypes, which is not yet BRG1 BRM (SW13 (VIM)) and the other expressing both (SW13 (vim +)) expresses. The presence of BRG1 and BRM SW13 correlates completely with the cell capacity, such genes, such as vimentin, collagenase, c-Met and CD44 expressed which is under the control of a transcription factor AP-1, which has previously been shown to require a functional complex SWI / SNF for its transactivation activity. Transitional treatment with histone deacetylase inhibitors to distinguish a stable transition SW13 (VIM) to a cell type induced SW13 (VIM +), suggesting that these two subtypes are different epigenetics. Run-on-analysis showed that, contrary to these four genes driven by AP-1 gene transcription and BRG1 BRM SW13 (VIM) can be initiated at a frequency comparable to SW13 (VIM +). In both cases SW13 (VIM) and SW13 (VIM +) cells were Brm BRG1 genes and transcribed by the entire gene with similar efficacy, indicating that their expression was completely suppressed at the post-transcriptional level SW13 (VIM) - cells. We suggest SW13 can spontaneously switch between two subtypes by changing the expression of BRG1 BRM and the post-transcriptional level.

Buy Human Oligodendrocyte Precursor Cells


Product Name: HOPC (human oligodendrocytes progenitor cells)

Specifications: 1 x 106 cells, 1 ml

Type: System CNS cell

Product Description:
HOPC be isolated from human brain tissue. HOPC cryopreserved at secondary culture and delivered frozen. HOPC are characterized by the immunofluorescence method with A2B5 and nestin antibodies.

1-Chlorobutane for sale

Product Name:1-Chlorobutane
Molecular Formula : CH3(CH2)3Cl
Appearance : Clear liquid with unpleasant odor
Molecular weight : 92.57
Density : 0.89 g/cm3@20°C
Melting points : -123°C
Boiling point : 77-79°C
Refractive index : 1.4015-1.4025
Flash point : -6°C
Water solubility : 0.066 g/L (30°C)
Application: Organic synthesis
Pharmaceutical intermediate
Packing: 175 Kgs / steel drums.
Transportation: UN NO. 1127
PACKING GROUP : ΙΙ
HAZARD CLASS : 3

2-Thiophene Acetic Acid for sale


Product name: 2-Thiophene Acetic Acid 
CAS no.:
 1918-77-0
Molecular Formula: C6H6O2S 
Molecular Weight: 
142.18
Appearance: White or light yellow scaly crystalline
Purity: ≥99%
Product description: Thiophene class.

Buy Ethylene Dichloride


Product Name: ethylene dichloride
CAS: 107-06-2
Molecular formula: C2H4Cl2
Molecular Weight: 98.96g / mol
Description:
Ethylene dichloride (EDC) is mainly in the production of vinyl chloride monomer (HSDB 2000) .It is also an intermediate in the production of hydrofluorocarbons and trichloroethane is used and is used as solvent.

Phenylacetaldehyde for sale


Product Name: phenylacetaldehyde
CAS: 122-78-1
Molecular formula: C8H8O
Formula Weight: 120.15
Description:
Phenylacetaldehyde is an aromatic compound found in buckwheat, chocolate and many other foods and flowers. It is also responsible for the antibiotic activity of maggot therapy and is a compound that is added to cigarettes to enhance flavor.
Many insects (Lepidoptera, Hymenoptera, Coleoptera and Neuroptera) use this substance for communication.

Buy N-Acetyl-D-tryptophan


The binding of three competitive inhibitors, N-acetyl-D-tryptophan has been studied, N-acetyl-L-tryptophan and amide N-acetyl-D-tryptophan, chymotrypsin on the pH range of 2 · 20-9 · 65 by the dialysis technique at equilibrium. 2. Within the limits of the experimental method, the binding of uncharged amide inhibitor is independent of pH in the range studied. 3. The connection of each enantiomer acids depends on the ionization of a group on the free enzyme, apparent pKa7 · 3. 4. It is shown that the results of the ionization group in the active site of the enzyme a net negative charge at pH above 7 · Development 3. 5. enzymes responsible groups are tentatively identified, and the importance of binding constants in terms of enzymatic catalysis is discussed.

Deuterated chloroform for sale


Product Name: deuterated chloroform
CAS: 865-49-6
Molecular formula: CCl3D
Formula Weight: 120.38
Description:
Deuterochloroform (CDCl3), a isotopologue chloroform (CHCl 3) in which the hydrogen ("H") with a deuterium (heavy hydrogen) is an isotope is replaced ("D"). Deuterated chloroform is the solvent most commonly used in NMR spectroscopy.

Deuterium oxide for sale


Product Name: deuterium oxide
CAS: 7789-20-0
Molecular formula: D 2 O
Molecular Weight: 8:03 p.m.
Description: deuterium oxide is water containing a higher than normal proportion of deuterium isotope of hydrogen.
The deuterium oxide is often used as a source of deuterium for preparing isotopologues specifically labeled organic compounds.

4-nitro-2-(trifluoromethyl)benzoic acid


Product Name: 2-nitro-4 (trifluoromethyl) benzoic acid
CAS: 320-94-5
Molecular formula: C8H4F3NO4
Formula Weight: 235.12
Description:
Density: 1.596 g / cm3
Melting point 134-138 ° C
Boiling point: 306.6 ° C at 760 mmHg
Flash Point: 139.2 ° C
Appearance: Yellowish crystals.
Application: Used as a pharmaceutical intermediate.
Storage: Stored in normal temperature.

Acenocoumarol for sale


Product Name: acenocoumarol
CAS: 152-72-7
Molecular formula: C19H15NO6
Molecular Weight: 353.33
Description:
Acenocoumarol is an anticoagulant, vitamin K antagonist (such as warfarin). It is a derivative of coumarin and is marketed under the brand name Sintrom and Sinthrome.

Glass beads plating iron and nickel


Product Name: Coating Glass Beads iron and nickel
Product description: glass beads is low density, high surface area, good thermal stability and chemical stability, high mechanical strength, good fluidity and other advantages, the main chemical composition is SiO2 and Al2O3. glass beads, although he himself does not have absorbent properties, but it is a good basic material for the production of glass beads absorbed .Have materials as the core, by electroplating on the surface of a layer good performance of the soft magnetic iron-nickel alloy or iron nanoparticles can not effectively reduce the density of the absorbent, but can also get good absorbent properties.

Diamond synthesis material - nickel coated graphite powder

Product Name: diamond synthetic material - nickel coated graphite powder

Product Description: Nickel coated graphite iron powder instead of accelerator mixture with the graphite powder and can be used in the synthesis of the diamond, effectively overcome the drawbacks that the catalyst uniformly mixing hard metal powder and powder graphite, and easily secrete after mixed. With the nickel-plated iron powder to remove the synthetic graphite piece product the metal continuity of graphite contact surface, easy to communicate when combing carbon atoms form at nucleation of the continuous metal film diamond, and contribute to the transformation diamond to improve the combination of synthetic diamond of high quality.

Synthetic diamond with carbonyl iron powder



Product Name: synthetic diamonds with carbonyl

Product Description: carbonyl is powder in the spherical and fine and high purity, uniform, low melting point, greater than the surface area, contact means with diamonds, which makes the preparation of powder catalyst high temperature graphite and vacuum reduction and the oxygen content down to less than 50 ppm, useful for diamond crystal growth in the ring, with respect to the catalytic synthesis routine, the diamond has a quality rate and a higher conversion.

NDT use carbonyl iron powder

Product Name: NDT use carbonyl iron powder

Product Description: 
brands of products used for testing the magnetic powder carbonyl iron powder 
 
No.
Mark
Average granularity
suspensibility
Fe
1
YT1
< 5
≥ 180
≥ 97.5
2
YT2
< 4
≥ 210
≥ 97.8
3
YT3
< 4
≥ 240
≥ 97.8
Note: Use the company's carbonyl iron powder as raw materials to produce flaw detection fluorescent powder, and comply with TB/T2600-96 standard requirement, the particle size head (air) method with measured, 100% 400 mesh sifting.

Methamphetamine price


Product Name: Methamphetamine
CAS: 537-46-2
Molecular formula: C10H15N
Molecular Weight: 149.233g / mol
Description: methamphetamine, also known as methamphetamine (DCI for +) form () known methylamphetamine, N-methylamphetamine, desoxyephedrine and colloquially as meth or "crystal meth," is a psychostimulant of the phenethylamine and amphetamine class drugs. It increases attention, concentration, energy and in high doses can cause euphoria, enhance self-esteem and increase libido.Methamphetamine high potential for abuse and dependence activation psychological reward system release a cascade of dopamine, noradrenaline and by the outbreak of serotonin in the brain,

2016年4月24日星期日

Red Sandalwood for sale


Product Name: red sandalwood
Description: red sandalwood has been traditionally used as a disinfectant or diuretic astringent, but lately it is used as a natural dye to dye mixtures of plants and
Toothpaste and has used one of the most popular natural dyes today.

What is Amikacin sulfate


Product Name: amikacin sulfate
CAS no. 39831-55-5
Molecular formula: C22H47N5O21S2
Molecular Weight: 781.76
Appearance: white crystalline powder
Product Description: Amikin is a aminoglycoside antibiotics. This antibacterial activity against Gram positive, Gram-negative bacteria and mycobacteria (including Mycobacterium tuberculosis), in particular significantly stronger effect aginst Escherichia coli, Pseudomonas aeruginosa and Proteus. It has the advantage that it stabilizes the enzyme to inactivate caused by a large number of Bacillus tract and Pseudomonas aeruginosa. It is for infection of non-susceptible bacteria to other aminoglycoside antibiotics appears.

6-APA price


Several penicillin producing fungi were tested for their ability to 6-aminopenicillanic acid (6-APA) and producing penicillin acylase. 6-APA was in the corn steep liquor fermentation Trichophyton mentagrophytes, Aspergillus ochraceus and three strains of Penicillium sp. 6-APA was not detected in fermentations Epidermophyton floccosum, although the penicillins have been produced. 6-APA is produced, a large proportion of the total production of antibiotics by T. mentagrophytes. The types of fungi produced by various penicillins were identified by paper chromatography and it was found that all the cultures prepared benzylpenicillin. T. mentagrophytes and A. ochraceous showed yield of benzylpenicillin phenoxymethylpenicillin and the formation in response to the addition to the medium of fermentation of phenylacetic acid and phenoxyacetic increase, respectively. mycelium washed three Penicillium spp. and two high-yield strains of P. chrysogenum had penicillin acylase activity of penicillin against phenoxymethylpenicillin. A. ochraceous, T. mentagrophytes E. floccosum and Cephalosporium sp. had activity against penicillin acylase phenoxymethylpenicillin. Only two of the above fungi, T. mentagrophytes and E. floccosum, showed significant activity against penicillin acylase benzylpenicillin; in both cases, it was very low. The acylase activity of A. ochraceous was significantly increased by culturing in the presence of phenoxyacetic. It is concluded that the 6-APA often, but not always accompanied by the formation of penicillin and penicillin-acylase activity against phenoxymethylpenicillin is in fungi producing penicillin.

2016年4月14日星期四

SK-OV-3 for sale


Product Name: SK-OV-3
human race
Source: ovarian adenocarcinoma, ascites transfer.
Morphology: epithelial
Medium and additives:
Containing 1.5 mM L-glutamine and 2.2 g sodium bicarbonate / l in McCoys 5a, the addition of fetal bovine serum to 10%.
Application: For research use only
Product Description:
SK-OV-3 was a 64 year-old white in female patients with ovarian cancer ascites G. Trempe and gold and 1973 cells are isolated tolerant to tumor necrosis factor and multiple cytotoxic drugs, including toxin diphtheria, cisplatin and adriamycin.

Prolactin(PRL)


Product Name: Prolactin (PRL)

Type: Other biological products

Product Description:
Prolactin (PRL) or Luteotropic hormone (LTH) is a peptide hormone discovered by Dr. Henry Friesen, primarily associated with lactation. Silently, stimulates the act of a child sucking the nipple, the production of prolactin, the breast with milk via a process called lactogenesis filled in preparation for the next feed.

Substance P for sale


Product Name: Substance P

CAS Registry Number: 33507-63-0

Molecular formula: C63H98N18O13S

Product Description:
In neuroscience, substance P (SP) is a neuropeptide: an undecapeptide which acts as a neurotransmitter and as neuromodulator.It belongs to the tachykinin family of neuropeptide. Substance P and neuropeptides are closely related neurokinin A (NKA) consisting of a polyprotein precursor by differential splicing of the preprotachykinin gene.

function:
Substance P is an important element in the perception of pain. Sensory function of the substance P is believed that the transmission of pain-related information to the central nervous system. Substance P coexisting with glutamate, an excitatory neurotransmitter in primary afferents that respond to painful stimulation.SP has been implicated in the regulation of mood disorders, anxiety, stress, reinforcement, neurogenesis, respiratory rate, neurotoxicity, nausea / vomiting, pain and nociception.

Ceftiofur HCl price


Product Name: Ceftiofur HCl
CAS-No. 103980-44.5
Molecular formula: C19H17N5O7S3Cl
Molecular Weight: 560.03
Product Description: antibiotics. It is mainly used for the treatment of bacterial respiratory diseases in pigs.

Mephedrone suppliers


Product Name: Mephedrone
CAS: 1189805-46-6
Molecular formula: C11H15NO
Molecular Weight: 177.242g / mol
Description: Mephedrone is a stimulant and entactogen synthetic drug amphetamine and cathinone classes.It in the form of tablets or powder comes, can swallow with the user, snort or inject, the effects similar to MDMA, amphetamines and cocaine.

Where to buy Botulinum toxin


Product Name: Botulinum toxin
CAS: 93384-43-1
Molecular formula: C6760H10447N1743O2010S32
Molecular Weight: 149322.3223 kDa
Description:
Although botulinum toxin is lethal naturally occurring substance, it can be used as effective and powerful medication.It a protein that is produced by the bacterium Clostridium botulinum, and is extremely neurotoxic.

Stigmasterol for sale


A collaborative study was conducted to evaluate a method for the determination of campesterol, stigmasterol and beta-sitosterol in saw palmetto raw materials and food supplements at concentrations> 1.00 mg / 100 g of a sample of 2 -3 g based. The test samples were hydrolyzed at high temperature with a solution of ethanolic KOH. Insaponifiable phytosterols (campesterol, stigmasterol and beta-sitosterol) was extracted with toluene. Phytosterols were derivatized ethers trimethylsilyl then quantified by gas chromatography with detection by flame ionization of hydrogen. Twelve blank samples, one of which was attached, were tested successfully with 10 employees. Recoveries obtained for the sample that has been set. The results were 99.8, 111 and 111% for campesterol, stigmasterol and beta-sitosterol, respectively. For repeatability relative standard deviation (RSDr) was 3.93 to 17.3% for campesterol, 3.56 to 22.7% for stigma and 3.70 to 43.9% for beta-sitosterol. RSDR for reproducibility was 7.97 to 22.6%, from 0 to 26.7% and from 5.27 to 43.9% for campesterol, stigmasterol and beta-sitosterol, respectively. Overall, the study leader approved 5 materials with acceptable values ​​for HORRAT campesterol, stigmasterol and beta-sitosterol from 1.02 to 2.16 range.

5-Cyanoindole Abstract

The nitrile bandwidth (CN) of 5-Cyanoindole tryptophan stretching vibration is a significant expansion upon hydration. So it was a useful infrared sensor hydration of the local environment of proteins are suggested. the spectral broadening results However, the molecular mechanism of this hydration is induced in uncoated function known experimental are difficult interpretation. We examine how the interaction of water with different locations of 5-Cyanoindole, the side chain of tryptophan 5-cyano affecting C N stretching a molecular electronic structure combined approach / dynamic. It should be noted that in addition to these interactions with the nitrile, water interactions with the indole ring to play an important role in mediating the C = N stretching. Thus, this study provides a molecular basis to understand how the hydration is C≡N band 5-cyanotryptophan elongation. In addition, an empirical model, which includes the interaction of both the nitrile and indole groups of water, was developed for the prediction of the stretching band C≡N by molecular dynamics simulations.

3,4-Dimethoxy Phenylethylamine


Product name:3,4-Dimethoxy Phenylethylamine
CAS: 120-20-7
Molecular Formula:C10H15NO2
Formula Weight:     181.23
Description:
Melting point:12-15 ºC
Boiling point:324.1 ºC at 760 mmHg
Flash Point:132.8 ºC
Density:1.074 g/mL at 25 °C(lit.)
Chemical property:Colorless transparent liquid.Soluble in water.
Use:Used as an intermediate in the organic synthesis.

2016年4月13日星期三

MDA-MB-157


Product name:MDA-MB-157
Species:Human

Gender:Female  

Source:Breast

Morphology: epithelial 

Growth Properties:Adherent growth

Application:
It can be used for breast cancer research.

Culture Media: DMEM, 10%FBS

Halofuginone

Product Name:Halofuginone
CAS:55837-20-2
Molecular Formula:C16H17BrClN3O3
Molecular weight:414.6815
Description:7-bromo-6-chloro-3-{3-[(3R)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one; 7-bromo-6-chloro-3-[3-(3-hydroxypiperidin-2-yl)-2-oxopropyl]quinazolin-4(3H)-one; 7-bromo-6-chloro-3-{3-[(2S,3R)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one; 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one