Product name:Zileuton
CAS: 111406-87-2
Molecular Formula: C11H12N2O2S
Molecular Weight: 236.29
Product description:2 - acetyl benzo [b] thiophene (Ⅰ) soluble in pyridine - ethanol (1:1) solution, adding hydroxylamine hydrochloride reaction at room temperature. And then to produce oxime (Ⅱ) ethanol solution with borane - pyridine complex, again add 20% ethanol solution of hydrogen chloride, reduction by hydroxylamine (Ⅲ). (Ⅲ) into dioxane trimethyl silicon alkyl isocyanate, heating for products.Can selectively inhibit 5 - lipoxygenase biosynthesis, used for asthma.
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