2016年1月25日星期一

9-Hydroxyrisperidone for sale

Product Name:9-Hydroxyrisperidone
CAS:144598-75-4
Molecular Formula:C23H27N4O3F
Molecular weight:  426.490783
Description:4h-pyrido(2,1-a)pyrimidin-4-one,6,7,8,9-tetrahydro-3-(2-(4-(6-fluro-1,2-benzis;oxazol-3-yl)-1-piperidinyl)ethyl)-9-hydroxy-2-methyl-;r76477;9-HYDROXYRISPERIDONE;Paliperidone;rac9-Hydroxyrisperidone;6,7,8,9-Tetrahydro-3-(2-(4-(6-fluro-1,2-benzisoxazol-3-yl)-1-piperidinyl)ethyl)-9-hydroxy-2-methyl-4H-pyrido[2,1-a]pyrimidin-4-one;Paliperidone for research

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Nebido for sale

Product name:Nebido
Description:Nebido is a sexual enhancement product administered via injection therapy, and marketed towards men who would like to boost their testosterone levels and sex drive. According to the company, the prescription-based drug may facilitate the restoration of normal, healthy testosterone levels in men who may be suffering from the adverse effects of low testosterone.
For more, please click:http://www.chemicalspharm.com/New-Products/Nebido/

For astronomers repeated sexual harassment

Scientists many sexual harassment cases occurring in American universities attracted the attention of a congressman. Mr Jackie Speier said she would appeal to strengthen the legal development of anti-sex discrimination to address similar problems. However, she advocated solutions - there is still no complete framework - can play to solve the problem of whether the effect is still unknown.

Last week, Speier external display details of the investigation more than a dozen years ago, on the University of Arizona astronomer Timothy Slater cases of sexual harassment, which became the day's headlines.

In 2005, the University of Arizona school management believes Slater alleged sexual harassment, and work environment resulting in an extremely bad influence. Speier disclosed in detail, Slater at work spreading insulting sex joke, visit a strip club at lunch, on the female colleagues insulting comments, and obscenity female students and so on. Although Slater denied some of the details, but still acknowledge the vast majority of them, according to the survey report, Slater consider themselves too "sexual initiative."年 2008, Slater left the University of Arizona and came to the Wyoming State University as director of science education.

Speiers the disclosure of Slater cases occurred in another three months after cases of sexual harassment together university (the University of California at Berkeley astronomer Geoffrey Marcy years on suspicion of sexual harassment of female students accept the school investigation and eventually resigned) exposure, but there is another together campus sexual harassment cases

Calcium orotate


Product name:Calcium orotate 
CAS:22454-86-0
Molecular formula:C10H8CaN4O9 
Molecular weight:368.27 
Product description: it is hardly soluble in water and practically insoluble in 96% Ethanol and Ether. This chemical is white to almost white crystalline powder.
For more, please click:http://www.chemicalspharm.com/products/Pharmaceutical-Intermediates/Calcium-orotate/

What is Flurbiprofen


CONTEXT:
The purpose of the study was to investigate the analgesic effect of a combination of flurbiprofen axetil intravenously and the relationship between opioid refractory pain relief levels and plasma β-endorphin in cancer patients and evaluate.
MATERIAL AND METHODS:
A total of 120 cancer patients were randomly divided into two groups, 60 patients took oral sulfate morphine sustained release tablets in Group A, and 60 other patients, combination treatment of axetil and opioids Intravenous flurbiprofen in group B. After 7 days, pain relief improves the quality of life and side effects were evaluated. In addition, β-endorphin plasma levels were measured by radioimmunoassay.
RESULTS:
With the combined treatment of axetil intravenous opioids and intravenous flurbiprofen, the total effective rate of pain relief has increased to 91.4% compared to 82.1% in the extended-release morphine sulfate tablet was used alone. Compared with group A, the analgesic effect in group B (p = 0.031) increased. He was also a satisfactory pain relief with a significant increase in plasma β-endorphin levels. After treatment, β-endorphin plasma levels in group B 62.4 ± 13.5 pg / ml, which is higher than in group A (45.8 ± 11.2 pg / ml) (p < 0.05).
CONCLUSION:
Our results suggest that the combination of intravenous flurbiprofen axetil and opioids may enhance the analgesic effect of opioids by increasing the levels of plasma beta-endorphin, which would give a selected and reliable strategy for the management of refractory cancer pain.

Polacrilin Potassium

Product name:Polacrilin Potassium
CAS:39393-76-5
Description:Polacrilin Potassium is typically used as a tablet disintegrant.It is the potassium salt of a unifunctional low-cross-linked carboxylic cation-exchange resin prepared from methacrylic acid and divinylbenzene.

from:http://www.chemicalspharm.com/New-Products/Polacrilin-Potassium/

2016年1月21日星期四

methyl propionate


All kinds of ring A stereoisomers of 2-methyl-1 alpha, 25-dihydroxyvitamin D (3) (2) and 20-epi-2-methyl-1 alpha, 25-dihydroxyvitamin D (3) (3) were synthesized by palladium catalysis. Kernel coupling reaction A "building blocks enin 'with CD-ring sections, the building block A-ring were made rationally through a novel and practical way, from methyl (R) - (+) - and ( S) - (-) -. 3-hydroxy-2-methyl-propionate, good yield X-ray crystallographic analysis 2alpha-methyl-1 alpha, 25-dihydroxyvitamin D (3) (2b) and the analysis of conformation the ring A of the 2alpha-methyl- (2b) and two methyl-1 beta and alpha ;, 25-dihydroxyvitamin D (3) (2f) is performed, and the results are described All diastereoisomers A-ring (2 and 3) , were synthesized and biologically evaluated both in vitro and in vivo .. The biological activity was highly dependent on the stereochemistry of the substituents A-ring. In particular, 4 times 2b showed high levels of the vitamin D receptor [VDR ] binding activity as the natural hormone and its 20-epimer (3b) showed high activity 12 times more potent in binding VDR, 7 times in the mobilization of calcium and 590 times in inducing differentiation of human leukemia promyelocytic (HL-60) cell relative to the natural hormone. In addition, the 20-epi-2beta-Me-1beta, 3alpha (OH) (2) isomer (3g) have significant biological activity relative to the natural hormone, in spite 1beta-OH-configuration. The activities of the transcription promoter of human osteocalcin, including VDRE in transfected mammalian cells were also evaluated. Finally, there was a clear contrast between the group of 2-methyl effects on HL-60 cell differentiation and apoptosis inducing activity. 2 and 3