What is Inhoffen Lythgoe diol

Product name:Inhoffen Lythgoe diol

CAS:64190-52-9

Molecular Formula:C13H24O2

Formula Weight:212.33g/mol

Description:Inhoffen Lythgoe diol is used as intmediate for VD Analog APIs or VD NCEs.

Maxacalcitol price

Product Name: maxacalcitol

CAS: 103909-75-7

Molecular formula: C26H42O4

Formula Weight: 418.61 g / mol

Description: maxacalcitol is used as a medication for secondary hyperparathyroidism by intravenous administration, and the inhibitory effects of PTH synthesis and secretion are applied in this case. And maxacalcitol is used as a medication for hyperkeratosis such as psoriasis vulgaris by percutaneous administration, and suppression of proliferation and differentiation of epidermal relief to be applied in this case.

Ferrous Saccharose price

Product name:Ferrous Saccharose

CAS:8047-67-4

Molecular Formula:C18H24Fe2O24

Molecular Weight:736.06g/mol

Description:Iron sucrose, also known as iron saccharate, is a complex of polynuclear iron (III)-hydroxide in sucrose for intravenous use.

Anthracene Brown for sale

Product Name: anthracene Brown
CAS: 602-64-2
Molecular Formula: C14H8O5
Molecular Weight: 256.21 g / mol
Description: Anthracene is a solid polycyclic aromatic hydrocarbon consisting of three rings of benzene, derived from coal tar. Anthracene is used in the artificial production of alizarin red dye. It is also found in certain coal tar oils, for example used as wood preservatives, insecticides and coating materials.

Dehydrocostus lactone

Product name:Dehydrocostus lactone
CAS:477-43-0
Molecular Formula:C15H18O2
Formula Weight:230.3
Description:
Boiling point:383.7 °C at 760 mmHg
Flash Point:161.2 °C
Density:1.09g/cm3|
Appearance:white powder.
Use:Serve as intermediates of medicine.
Storage:Store at room temperature.

Schisandrin A price

Product Name: schisandrine A
CAS: 61281-38-7
Appearance: colorless crystalline powder
Application: All our products are only for research and laboratory. Injecting, food and other means are prohibited.
Purity: ≥98%
Molecular formula: C24H32O6
Molecular Weight: 416.51
Description: Soluble in ethyl acetate, acetone, methanol, insoluble in water. Astringing lungs to stop coughing, Gripping perspiration, Engender liquid, hemostasis, Tranquilisierung, toning kidney.

Effects of salvianolic acid B and tanshinone IIA

Losartan (LST) is a common chemical drug that is used to treat high blood pressure and reduce the risk of stroke in some people suffering from heart disease. Danshen, prepared from the dried root and rhizome of Salvia miltiorrhiza Bunge, has been widely used for the prevention and treatment of various cardiovascular and cerebrovascular diseases. There are more than 35 formulations with Danshen indicated in the Chinese Pharmacopoeia 2010, which are often combined with LST to treat cardiovascular and cerebrovascular diseases in the clinic. The effects of the two main components of Dansen, salvianolic acid B (SA-B) and Tanshinon IIA (Tan IIA) on the pharmacokinetics of losartan and its metabolites in rats were EXP3174 by liquid chromatography with mass spectrometry (LC clerk). Sprague-Dawley rats were randomly assigned to 3 groups: LST, LST + the main pharmacokinetic parameters SA-B and LST + Tan IIA, and were estimated by oral administration of LST, LST + SA-B and LST + Tan IIA. It was found that there were significant differences in the pharmacokinetic parameters between the three groups: the LST + SA-B group was Cmax, t1 / 2, AUC, AUMC lower than that in the LST group then more in the LST group + Tan IIA. In addition, the effects of SA-B and II Tan on losartan metabolism were also examined using rat liver microsomes in vitro. The results showed that SA-B can induce LST Tan metabolism while IIA can inhibit LST metabolism in rat liver microsomes in vitro by regulating the activities of CYP450 enzymes. In addition, the effect of SA-B and Tan AII on CYP3A4 and CYP2C9 expression in Chang hepatic cells was examined by Western blotting and real-time PCR. It has been noted that the two components of Danshen, SA-B and Tan IIA different influences have on LST metabolism: SA-B can obviously speed up LST metabolism by inducing CYP3A4 / 2C9 activities and production, however, Tan IIA slow down the metabolism of LST by inhibiting CYP3A4 / 2C9 activities.