2017年6月10日星期六

Apremilast

Product name:Apremilast
CAS
: 608141-41-9
Molecular Formula: C22H24N2O7S
Molecular Weight: 0
Product description:An oral, selective phosphodiesterase 4 (PDE4) inhibitors, name of commodity Otezla, the drug is approed by FDA first type is the only one for Plaque Psoriasis treatment of PDE4 inhibitor, is used to fit phototherapy and systematic treatment of moderate to severe Plaque Psoriasis (Plaque Psoriasis), the treatment of adult patients.

3-Acetylpyridine

Product name:3-Acetylpyridine
CAS
: 350-03-8
Molecular Formula: C7H7NO
Molecular Weight: 121.1366
Product description:Colorless to yellow liquid. In peanuts and nuts like aroma, as the smell of popcorn, has a sweet taste. The boiling point of 230 ℃. Soluble in acids, ethanol, ethyl ether and water.As a treatment for osteoporosis drugs, plug the intermediates of phosphonic acid sodium; Pesticide intermediates.Spices. Mainly used for preparation of popcorn, peanut, meat and tobacco flavor.
 

2,5-Dichloronitrobenzene

Product name:2,5-Dichloronitrobenzene
CAS
: 89-61-2
Molecular Formula: C6H3CI2NO2
Molecular Weight: 192.00
Product description:Paracide by mixed acid nitration, the reaction products are washed, neutralization, separation for a quick finished product. Mainly used for 2, 5 - dichloro nitrobenzene with phenol condensation, reduction of available chlorine 2 - amino - 4 - diphenyl ether, this also is a kind of dye intermediates, can be used in the synthesis of weak acid red B dye, etc., can also be used as a nitrogen fertilizer synergist.

Nebivolol hydrochloride

Product name:Nebivolol hydrochloride
CAS
: 152520-56-4
Molecular Formula: C22H25F2NO4HCL
Molecular Weight: 441.9
Product description:Of the third generation is a potent and selective beta-blockers, the strength of the block 1 receptor beta for beta 2 receptor 290 times, and the peso bisoprolol for 26 times, atenolol is 15 times, general naylor is 1.9 times. So this product has higher selectivity, does not cause bronchial smooth muscle and vascular smooth muscle contraction, not endogenous to the sympathetic activity.Impact on cardiac function and hemodynamics, nai will bisoprolol has no obvious negative inotropic effect, on the contrary, it has certain protective effect to the cardiac function, can reduce cardiac preload, and cardiac afterload unchanged or slightly down. Application of nai will los then can increase ejection fraction in patients with heart failure, and pulmonary artery pressure and pulmonary capillary pressure has no obvious change.

Flutrimazole

Product name:Flutrimazole
CAS
: 119006-77-8
Molecular Formula: C22H16F2N2
Molecular Weight: 346.3726
Product description:Suitable for flocculent by favus bacteria, dog microspore bacteria and skin tinea bacteria caused by fungal infection, such as brothers tinea, tinea, tinea, tinea versicolor, tinea capitis, onychomycosis, facial ringworm, tinea and topical treatment of vulvitis. Also applies to candida yeast candida infection and noise pityriasis caused by skin. Mechanism is by inhibiting fungi activity of cytochrome P - 450 which inhibits fungal cell membrane on ergosterol biosynthesis, damage fungi and change the permeability of cell membrane, thus inhibiting the growth of fungi. The IC50 alue concentration of 0.071 mu mol/L. As to the cause of animal and human saprophytic and pathogenic ringworm bacteria, filamentous fungi and yeasts have strong inhibition, most of the test strains the minimum inhibition concentration of 0.025 5.0 mu in g/ml. Its curative effect, side effect is small.

Flutrimazole

Product name:Flutrimazole
CAS
: 119006-77-8
Molecular Formula: C22H16F2N2
Molecular Weight: 346.3726
Product description:Suitable for flocculent by favus bacteria, dog microspore bacteria and skin tinea bacteria caused by fungal infection, such as brothers tinea, tinea, tinea, tinea versicolor, tinea capitis, onychomycosis, facial ringworm, tinea and topical treatment of vulvitis. Also applies to candida yeast candida infection and noise pityriasis caused by skin. Mechanism is by inhibiting fungi activity of cytochrome P - 450 which inhibits fungal cell membrane on ergosterol biosynthesis, damage fungi and change the permeability of cell membrane, thus inhibiting the growth of fungi. The IC50 alue concentration of 0.071 mu mol/L. As to the cause of animal and human saprophytic and pathogenic ringworm bacteria, filamentous fungi and yeasts have strong inhibition, most of the test strains the minimum inhibition concentration of 0.025 5.0 mu in g/ml. Its curative effect, side effect is small.

Flutrimazole

Product name:Flutrimazole
CAS
: 119006-77-8
Molecular Formula: C22H16F2N2
Molecular Weight: 346.3726
Product description:Suitable for flocculent by favus bacteria, dog microspore bacteria and skin tinea bacteria caused by fungal infection, such as brothers tinea, tinea, tinea, tinea versicolor, tinea capitis, onychomycosis, facial ringworm, tinea and topical treatment of vulvitis. Also applies to candida yeast candida infection and noise pityriasis caused by skin. Mechanism is by inhibiting fungi activity of cytochrome P - 450 which inhibits fungal cell membrane on ergosterol biosynthesis, damage fungi and change the permeability of cell membrane, thus inhibiting the growth of fungi. The IC50 alue concentration of 0.071 mu mol/L. As to the cause of animal and human saprophytic and pathogenic ringworm bacteria, filamentous fungi and yeasts have strong inhibition, most of the test strains the minimum inhibition concentration of 0.025 5.0 mu in g/ml. Its curative effect, side effect is small.