2017年6月10日星期六

Adenosine diphosphate

Product name:Adenosine diphosphate
CAS
: 58-64-0
Molecular Formula: C10H15N5O10P
Molecular Weight: 427.2
Product description:By a molecule are connected to the two adenosine phosphate compound of root, is a kind of nucleotide. In the organism, usually in the form of adenosine triphosphate (ATP) hydrolysis lose a phosphoric acid root, namely a high-energy phosphate bond rupture, and after the release of energy products. When an ATP molecule of phosphoric acid root fracture, hydrolysis can produce adenosine diphosphate, and release 7.3 kcal of energy. On the contrary, adenosine diphosphate and phosphate radical reaction produces adenosine triphosphate (energy absorption). During photosynthesis endergonic process have this reaction. Formula: ADP + Pi + energy = (ATP enzyme involved in) (reaction) store energy, energy absorption Is the earliest, it was found that also is the most important induced platelet aggregation substance in the body. In vitro experiments can be observed that the two types of platelet aggregation induced by ADP. ADP exists in platelet cells density particles, when the platelet coagulation reaction is released, ADP on the platelet ADP receptor affect platelet shape and biological behavior.

Sumatriptan Succinate

Product name:Sumatriptan Succinate
CAS
: 103628-46-2
Molecular Formula: C14H21N3O2S
Molecular Weight: 295.4
Product description:This product is a migraine drug resistance, is a highly selective serotonin receptor agonists (5 - HT), reverse migraine intracranial vascular expansion, reduce plasma protein extravasation, improve cerebral blood flow, relieve the symptoms of migraine. For the treatment of acute migraine attacks. Oral works faster than the ergotamine caffeine, efficient was 66%, higher than ergotamine caffeine; Can also be used for the treatment of cluster headache (ch), 15 to 30 minutes of efficient was 74% ~ 77%.

4-Anisicacid

Product name:4-Anisicacid
CAS
: 100-09-4
Molecular Formula: C8H8O3
Molecular Weight: 152.15
Product description:Colorless needle crystal, soluble in ethanol, ethyl ether, chloroform, slightly soluble in hot water, hardly soluble in cold water.For spices and pharmaceutical industry.As an antiseptic and raw material of medicine and spice.Used for tomato raschig, ethylamine sulfonated ketone of skin, such as pharmaceutical intermediates, can be used for spices.

Cyclopentolate hydrochloride

Product name:Cyclopentolate hydrochloride
CAS
: 5870-29-1
Molecular Formula: C17H26ClNO3
Molecular Weight: 327.85
Product description:This product is a synthetic fight choline medicine, by blocking the iris sphincter and ciliary muscle responses to cholinergic agonist, thus make the pupil grow larger and ciliary muscle paralysis. This product quickly, but the effect time, shorter than atropine, dropping after 25 minutes to 75 minutes maximum cycloplegia, usually 6 to 24 hours after dropping regulation fully recovered.This product may interfere with kappa choline, jaborandi alkali glaucoma; With cholinesterase inhibitors of ophthalmology share, this product can adersely affect these agents of glaucoma and shrink the pupil.

Timclol Maleate

Product name:Timclol Maleate
CAS
: 26921-17-5
Molecular Formula: C17H28N4O7S
Molecular Weight: 432.49
Product description:1. Used for primary hypertension, of mild and moderate hypertensive curative effect is better, but with diuretics share; 2. Coronary heart disease (CHD) and can be used for the treatment of angina and myocardial infarction; 3. Used for tachycardia; 4. Prevent migraine; 5. This medicine eye drops for the treatment of glaucoma, especially applicable to the primary, primary open-angle glaucoma, curative effect is superior to the traditional effects in medicine. Can also be used for angle-closure glaucoma after operation, no crystal glaucoma, some secondary glaucoma, high intraocular pressure and the invalid glaucoma drugs and surgery. But with pupil medicine combined application.
 

Ezetimide

Product name:Ezetimide
CAS
: 163222-33-1
Molecular Formula: C24H21F2NO3
Molecular Weight: 409.43
Product description:A novel selective cholesterol absorption inhibitor, was also the first selective inhibitor of intestinal cholesterol absorption, its mechanism of action and other lipid-lowering drugs.This product with small intestinal brush border membrane capsule on the bubble membrane protein (145 x103 relative molecular mass), inhibition of small intestine of the cholesterol in the diet and the bile to the intestinal absorption, reduce the cholesterol in the serum and liver.

What is Dabigatran Etexilate

Product name:Dabigatran Etexilate
CAS
: 872728-81-9
Molecular Formula: C34H41N7O5.CH4O3S
Molecular Weight: 723.84
Product description:Belong to non peptide thrombin inhibitors, through specific and selective blocking thrombin (free type or a combination of type) activity and the anticoagulant effect into full play. Can be oral, powerful, no special drug monitoring, low drug interaction, this is anticoagulant therapy field and potentially fatal thrombosis prevention, a significant progress in the field of landmark. Oral after gastrointestinal absorption in the body into a anticoagulant activity of pekah group directly, by combining the thrombin fibrin specific binding sites, prevent fibrinogen cracking for fibrin, thereby blocking the blood coagulation cascade network last step and thrombosis. Darby added group from fibrin one thrombin combination turned away from, give play to the role of reversible anticoagulation.