2019年3月21日星期四

Trimetazidine

Product name:Trimetazidine
CAS: 5011-34-7
Molecular Formula: C14H22N2O3
Molecular Weight: 266.34
Product description:A piperazine derivatives, commodity called great force, chemical name of 1 - (2 and 4 - preparation benzyl) piperazine hydrochloride, two for the angina pectoris medicine. Against epinephrine, norepinephrine, and the effect of vasopressin, can directly relax vascular smooth muscle, reduce vascular resistance, increase the flow of blood to the coronary artery and peripheral circulation and promoting myocardial metabolism and energy production. At the same time reduce the myocardial oxygen consumption and improve myocardial oxygen supply and demand balance. Can increase the tolerance of cardiac glycoside, also can increase the exercise tolerance test of angina patients, significantly reduce angina frequency, reduce the dosage of nitroglycerin. Clinical used in the treatment of coronary artery insufficiency, angina pectoris and old myocardial infarction; For those with severe cardiac insufficiency with digitalis.

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