2016年1月19日星期二
Stugeron Introduction
It was suggested that the increase in viscosity reducing blood flow in the capillaries, with a consequent improvement of symptoms of patients with peripheral vascular disease. We studied the effect of treatment with drugs allegedly to reduce the viscosity of blood, to test the validity of this claim. Tetra nicotinoyl fructose (Bradilan) oxpentifylline (Trental) and cinnarizine (Stugeron) - viscosity measurements and the speed of the leg blood flow were found in a group of patients and taken after treatment with three different drugs. All patients had lameness in the leg and the distribution of arteriosclerosis was in each patient. After treatment, there was little or no change in blood viscosity is recorded and no change in the flow velocity in symptomatic legs. We found no objective evidence that the use of these drugs in patients with intermittent claudication find support.
What is Prulifloxacin
Prulifloxacin, gatifloxacin is oral fluoroquinolone antibiotics. After the absorption, the prodrug active metabolites through. The drug has the elimination half-life, to allow once-daily dosing. You Lisha star is usually more active than other fluoroquinolones in vitro a variety of clinical isolates of Gram-negative bacteria, including community and hospital C OLI suppressed by the pathogenic strains of Haemophilus influenzae 90%, deformation cloacae, Providencia Providencia neighborhood island and suppress Serratia, catarrhal Haemophilus Moraxella for You Lisha star activity against Pseudomonas aeruginosa vary by country. Gram-positive organisms such as methicillin or oxacillin including MSSA Enterococcus (Enterococcusspp.) And Streptococcus pneumoniae Italian immigrant communities vulnerable ulifloxac. Spain active strains moderate pneumonia. In well-designed clinical trials, as well as good clinical, bacteriological efficacy (similar to ciprofloxacin, amoxicillin or significantly Pefloxacin <50kg600 prulifloxacin 10 days with acute exacerbation of chronic bronchitis or complex under Urinary tract infections (UTIs), a single dose of 600mg acute prulifloxacin, not complicated at UT. two kinds Prulifloxacin clinical trials are usually well tolerated, signings also possible ciprofloxacin resistance.
Tetramethylpyrazine
Product name: Tetramethylpyrazine
CAS no.: 1124-11-4
Molecular Formula: C8H12N2
Molecular Weight: 136.19
Appearance: White crystal or powder
Product description: As a flavoring agent, the sweet taste of alcoholic beverages, the reinforcing agent of the cigarette, the reinforcing agent and the supplement of the cigarette.
For more, please click:sales@chemicalspharm.com
Where to buy Glucose -Beta- cyclodextrin
Product name:Glucose -Beta- cyclodextrin
CAS no.: 92517-02-7
Molecular Formula: C48H80O40
Molecular Weight: 1297.12
Appearance: White Powder
Purity: ≥98%
Product description:In Medical field, it can promotes the dissolusion efficiency of the drugs, enhancing bioavailability and solubility of drugs,so that to reduce the dose but increase the efficacy, mainly used in medicine of oral liquid.
"Magic pill" to inhibit pancreatic metformin progress
Researchers from Massachusetts General Hospital, found a new mechanism to inhibit pancreatic diabetes drug metformin progress, relevant research results were published in international journals Plos One.
For this study, the most common form of pancreatic cancer - pancreatic ductal adenocarcinoma were studied emphatically. Currently the United States has about 40,000 people each year die from the disease, and a diagnosis of pancreatic ductal adenocarcinoma patients in the presence of about half of overweight or obese, up to 80% of patients with type 2 diabetes or insulin resistance.
Studies have found that patients taking the diabetes medication metformin lower risk of suffering from pancreatic cancer, has been developed for patients with cancer and then taking metformin or may reduce the risk of death. But before this study scientists metformin it has been unclear how to resist the development of pancreatic cancer, nor found to respond to metformin potential biomarkers.
In this study, the researchers first found that for overweight or obese patients taking metformin for treatment, the tumor sample an extracellular matrix component - hyaluronic acid content than patients not taking metformin for 30% less. In obese mouse model of pancreatic cancer, it is possible to reduce the expression of Metformin 1 type hyaluronic acid and collagen, while the activation of pancreatic stellate cells (PSC) is also less. The researchers used cultured cells to study found that metformin can inhibit signaling pathways PSC for the synthesis of hyaluronic acid and Type 1 collagen, but also prevents recruitment of tumor-associated macrophages.
For this study, the most common form of pancreatic cancer - pancreatic ductal adenocarcinoma were studied emphatically. Currently the United States has about 40,000 people each year die from the disease, and a diagnosis of pancreatic ductal adenocarcinoma patients in the presence of about half of overweight or obese, up to 80% of patients with type 2 diabetes or insulin resistance.
Studies have found that patients taking the diabetes medication metformin lower risk of suffering from pancreatic cancer, has been developed for patients with cancer and then taking metformin or may reduce the risk of death. But before this study scientists metformin it has been unclear how to resist the development of pancreatic cancer, nor found to respond to metformin potential biomarkers.
In this study, the researchers first found that for overweight or obese patients taking metformin for treatment, the tumor sample an extracellular matrix component - hyaluronic acid content than patients not taking metformin for 30% less. In obese mouse model of pancreatic cancer, it is possible to reduce the expression of Metformin 1 type hyaluronic acid and collagen, while the activation of pancreatic stellate cells (PSC) is also less. The researchers used cultured cells to study found that metformin can inhibit signaling pathways PSC for the synthesis of hyaluronic acid and Type 1 collagen, but also prevents recruitment of tumor-associated macrophages.
Where to buy Phytine
Product name:Phytine
CAS: 7776-28-5
Molecular Formula:C6H6Ca6O24P6
Formula Weight:888.41
Description:
This product is light yellow slurry liquid, soluble in water, ethanol, acetone, insoluble in anhydrous ether, benzene, hexane, chloroform.
Phytine is used as chelating,antioxidant,antistaling agent,and water softener etc,and is widely used in food,medicine,painting and chemical industry for daily use.
From:http://www.acridine-raw-material.com/products/Phytine/
Evolutionary Game animal sex organs
For decades, scientists have collected a lot of information about the diversity of animal penis, including straight, bifurcated, spiral, long a thorn. However, from the point of view of anatomy, physiological features females equally important to reflect information. Integration and comparative biology meeting held last week, scientists produced a male organ in a lively discussion. Among female sex organs and anatomical structures its importance in shaping the penis has also joined the discussion thread. "A lot of people think that is a kind of female sex after the meeting," evolutionary ecologist at the University of Utah reproductive Teri Orr said.
Scientists have studied the sharks, snakes, and physiological characteristics of other animals in this area. They found that female sexual organs in a complex structure something like the males. So they began to female deemed this "evolution contest" active participants. For example, females will evolve a more complex genitalia, thereby helping to control the mating behavior, while preventing the "strong on" behavior, but these features has led to further evolution of the male sex organs.
Thirty years ago, the field of comparative evolution "plug-in" by the evolutionary biologist biology of sexual organs William? Eberhard created, he was working on the diversity of male genitalia, including the character, size, surface decoration and so on. Eberhard wanted to know the reasons for these diversity. However, when he believed the female genitals, "about the same", which led other scientists to ignore its importance.
Professor Eberhard continue to study the flies, wasps, spiders and other species, are beginning to realize the female sexual organs may not be as easy as you think. Especially males of some species during mating with each other often make friction, tearing, or even chewing behavior, so as to prevent the female from the process. He therefore believed that females might have some preventive mechanism accordingly.
Bolise Co., Ltd.
Scientists have studied the sharks, snakes, and physiological characteristics of other animals in this area. They found that female sexual organs in a complex structure something like the males. So they began to female deemed this "evolution contest" active participants. For example, females will evolve a more complex genitalia, thereby helping to control the mating behavior, while preventing the "strong on" behavior, but these features has led to further evolution of the male sex organs.
Thirty years ago, the field of comparative evolution "plug-in" by the evolutionary biologist biology of sexual organs William? Eberhard created, he was working on the diversity of male genitalia, including the character, size, surface decoration and so on. Eberhard wanted to know the reasons for these diversity. However, when he believed the female genitals, "about the same", which led other scientists to ignore its importance.
Professor Eberhard continue to study the flies, wasps, spiders and other species, are beginning to realize the female sexual organs may not be as easy as you think. Especially males of some species during mating with each other often make friction, tearing, or even chewing behavior, so as to prevent the female from the process. He therefore believed that females might have some preventive mechanism accordingly.
Bolise Co., Ltd.
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