2016年6月22日星期三

Best Quality 4-Aminophenylarsonic Acid for sale

Product Name: best quality 4-acid Aminophenylarsonic
CAS: 98-50-0
Molecular formula: C6H8AsNO3
Molecular Weight: 217.0542
Properties: white crystalline powder
Solubility: soluble in water, slightly soluble in ethanol, insoluble in chloroform, ether.
Product Description:
1.Used reagent used in the manufacture of medicaments and for the determination of ammonium, cerium, zirconium.
2.2. feed antibiotics. Can promote, improve feed efficiency, animal growth. Having to kill bacteria, protozoa and function of Helix, particularly in the treatment of bacterial infections, poultry is its effect on the promotion of growth for pigs and chickens, etc.
The 3.4-Aminophenylarsonic acid is a fully synthetic antimicrobial agent. While legal and food additives authorized FDA.

High quality Streptozocin


Product Name: High quality Streptozocin
CAS: 18883-66-4
Molecular formula: C8H15N3O7
Molecular Weight: 265.22
Melting point: 121 ° C
Storage: -20 ° C
Product description: produced by streptococci, in mammals, B cells producing insulin from pancreatic islet cells have a specific toxicity of natural compounds, the type of glass antibiotic, it is different, with urea water glass in fats is ethyl, methyl chloride, to the other end, the molecule is an amino sugar streptozocin quality can decompose the active carbon ions and methylene crosslinks between DNA strands, so that the alkylation of DNA, but its lower than the alkylation of other drugs nitroso urea, Nokia corp. and urea nitrate metabolites alkylation of 3 ~ 4 times the STZ. STZ can form the isocyanate in the body.

2016年6月21日星期二

What is Isoquinoline

Parkinson's disease is believed to be caused by some unknown endogenous or exogenous factors that interact with genetic material. 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is a neurotoxin exogenous parkinsonism in humans, monkeys and different animals due to the monoamine oxidase type B Preparation of (MAO B) the reaction catalyzed in the pyridinium 1-methyl-4-phenyl-ion (MPP +), which selectively kills dopaminergic nigrostriatal neurons. Various isoquinoline derivatives have been in the brains of patients with Parkinson's disease. Isoquinoline neurochemical characteristics similar to MPTP, and they are called endogenous neurotoxins be the cause of Parkinson's disease. Among these tetrahydroisoquinoline (TIQ), 1-benzyl-TIQ and (R) -1,2-dimethyl-5,6-dihydroxy-TIQ [(R) -N-methyl-salsolinol)] have the most powerful neurotoxicity . ITQ that MPTP can be activated via the N-methylation of N-methyltransferase and oxidation MAO. QIT and MPP + I of the electron transport system complex to inhibit the mitochondria, thereby reducing the formation of ATP and the production of oxygen radicals. Although ITQ properties are similar to those of the MPTP neurotoxicity QIT is lower than that of MPTP. Since Parkinson's disease is a neurodegenerative disease slowly progressive, long-term neurotoxic effects of IQS remains to be studied in primates.

Lonidamine for sale


Product Name: lonidamine
CAS: 50264-69-2
Molecular formula: C15H10Cl2N2O2
Molecular Weight: 321.16
White to light yellow crystals, melting point 207 ℃, soluble in methanol and acetic acid acid.Narrow spectrum antitumor acid medicine: product description. Can be used for a variety of tumors, such as breast, prostate, lung and brain tumors, etc. In addition, also a type of kill sperm.

Buy Nifuroxazide

constitutive activation of STAT3 transcription factor contributes to the pathogenesis of many cancers, including multiple myeloma (MM). Since STAT3 is unnecessary in most normal tissues, inhibition of STAT3 target for patients with these cancers, an attractive therapy. To identify STAT3 inhibitors, we have developed a test based transcriptional and screened a library of compounds are known to be safe in humans. We found the drug nifuroxazide a potent inhibitor of STAT3 function. Nifuroxazide inhibits the constitutive phosphorylation of STAT3 in MM cells Jak kinase autophosphorylation reduced and results in a down regulation of the target gene STAT3 Mcl-1. Nifuroxazide caused a decrease in the viability of primary myeloma cells and cell lines of STAT3 activation myeloma includes, but not normal peripheral mononuclear blood cells. Although bone cell survival signals provide stromal marrow to myeloma cells may nifuroxazide to remedy this survival advantage. According to the interaction of STAT3 with other cellular pathways, shows increased cytotoxicity nifuroxazide combined if either the histone deacetylase inhibitor depsipeptide or MEK inhibitor UO 126. Therefore, a mechanistic screen based we have found clinically relevant drugs nifuroxazide a potent inhibitor STAT signaling, cytotoxicity against myeloma cells shows that depend for their survival on STAT3.

Ecabet sodium


Product Name: sodium Ecabet
CAS: 86408-72-2
Molecular formula: C20H27NaO5S
Molecular Weight: 402.48
Product Description: 1. The gastric mucosa covered protection: This product can with gastric mucosal injury in patients with a combined form of the membrane barrier to protect the gastric mucosa of the erosion of the gastric acid be selective. Effect on the gastric mucosal coverage is not affected by the change of pH in the stomach. 2. Activity pepsin inhibition: This product has inhibitory effects on healthy adults in the activity of pepsin. In combination with pepsin and pepsin, the drugs .A new type of gastritis, gastric ulcer treatment activity of pepsin in vitro (test) remember.

2016年6月7日星期二

Raltitrexed


Product Name: Raltitrexed
CAS: 112887-68-0
Molecular formula: C21H22N4O6S
Molecular Weight: 458.49
Product Description: thymus synthetase inhibitors, belongs to a kind of salt of folate analogues. In the radius of the curve connector body is shortly after that the cells actively participating folic acid polymerization as a series of glutamic acid, poly metabolism glutamate synthetase these metabolites as a ray of the song must be a stronger inhibitory effect of thymus synthase, wherein the DNA of the cells inhibit the synthesis and play retention within the cell for a long time a role of inhibition.