2018年9月14日星期五

Gnetol

Product name:Gnetol
CAS
: 86361-55-9
Molecular Formula: C14H12O4
Molecular weight:244.24688
Appearance:White crystalline powder
Stability:Stable
Shelf life:2 years
Product description :Gnetol is use as Pharmaceutical intermediates.

Enocitabine

Product name:Enocitabine
CAS
: 55726-47-1
Molecular Formula: C31H55N3O6
Molecular weight:565.78
Appearance:white powder
Stability:Stable
Shelf life:2 years
Product description :Enocitabine is a derivative of cytarabine that acts as a nucleoside analog of cytosine. Enocitabine is the a pro-drug of Ara-C and exhibits anticancer chemotherapeutic and antiviral activities. Like other nucleoside analogs, enocitabine is incorporated into DNA, preventing chain elongation and cell growth. Enocitabine is clinically used in some countries and is undergoing clinical trials in others as a potential treatment for leukemias and lymphomas such as acute myelogenous leukemia (AML).

Ubenimex

Product name:Ubenimex
CAS:
 58970-76-6
Molecular Formula: C16H24N2O4
Molecular weight:308.38
Appearance:white powder
Stability:Stable
Shelf life:2 years
Product description :Ubenimex is a competitive, reversible protease inhibitor. It is an inhibitor of arginyl aminopeptidase (aminopeptidase B),leukotriene A4 hydrolase (a zinc metalloprotease that displays both epoxide hydrolase and aminopeptidase activities),alanyl aminopeptidase (aminopeptidase M/N),leucyl/cystinyl aminopeptidase (oxytocinase/vasopressinase),and membrane dipeptidase (leukotriene D4 hydrolase). It is being studied for use in the treatment of acute myelocytic leukemia.
 

Lonidamine

Product name:Lonidamine
CAS:
 50264-69-2
Molecular Formula: C15H10Cl2N2O2
Molecular weight:321.1581
Appearance:white powder
Stability:Stable
Shelf life:2 years
Product description :Lonidamine is a derivative of indazole-3-carboxylic acid, which for a long time, has been known to inhibit aerobic glycolysis in cancer cells. It seems to enhance aerobic glycolysis in normal cells, but suppress glycolysis in cancer cells. This is most likely through the inhibition of the mitochondrially bound hexokinase.

Carfilzomib

Product name:Carfilzomib
CAS:
 868540-17-4
Molecular Formula: C40H57N5O7
Molecular weight:719.9099
Appearance:white powder
Stability:Stable
Shelf life:2 years
Product description :Carfilzomib is an anti-cancer drug acting as a selective proteasome inhibitor.For use in patients with multiple myeloma who have received at least two prior therapies, including treatment with bortezomib and an immunomodulatory therapy (such as lenalidomide) and have demonstrated disease progression on or within 60 days of completion of the last therapy.

Furosemide

Product name:Furosemide
CAS
: 54-31-9
Molecular Formula:C12H11ClN2O5S 
Molecular weight:330.74
Appearance:white powder
Stability:Stable
Shelf life:2 years
Product description :Furosemide is a medication used to treat fluid build-up due to heart failure, liver scarring, or kidney disease.It may also be used for the treatment of high blood pressure. The amount of medication required depends on the person in question.

Ketanserin

Product name:Ketanserin
CAS:
 74050-98-9
Molecular Formula: C22H22FN3O3
Molecular weight:395.43
Appearance:white powder
Stability:Stable
Shelf life:2 years
Product description :Ketanserin is a quinazoline derivative and serotonin (5-hydroxytryptamine, 5HT) receptor subtype 2 (5-HTR2) antagonist with potential antihypertensive and antiplatelet activities. Following administration, ketanserin binds to and inhibits the signaling mediated by 5-HTR2, which inhibits serotonin-dependent vasoconstriction and platelet activation.Used clinically as an antihypertensive agent and in scientific research to study the serotonin system; specifically, the 5-HT2 receptor family.