2016年8月2日星期二
Roxatidine price
Roxatidine is H (2) receptor antagonist is frequently used in the treatment of gastric ulcers. H (2) receptor blockers reported to show contraceptive activity. To investigate the mechanism of contraceptive, estrogenic and anti-estrogenic activity was studied using an in vitro assay using rat and rabbit uterine Uterotrophic test receiver and in vivo binding in immature Wistar rats. The results showed that roxatidine showed a slight receiver both in the rat and the rabbit uterine receptor binding affinity compared to estradiol. Interstingly, roxatidine in vivo increases the wet weight of the uterus of immature Wistar rats significantly (p <0.001) compared to a control group. The increase in uterine weight was treated in roxatidine group somewhat similar to that of the group treated with estradiol. Histopathological findings and the structure of the support roxatidine, which is H (2) receptor blockers roxatidine an estrogenic compound.
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