2016年2月2日星期二
How to buy NFS-60,for sale
Product name:NFS-60
Species:Rat
Specifications: strains
Product description:
NFS-60 cells were previously obtained from leukemia cells that were infected with the Cas-Br-M murine leukemia virus in vivo.
The NFS-60 cell line is a factor-dependent, bipotential hemopoietic cell line.
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tauroursodeoxycholicacid,TUDCA
Name: tauroursodeoxycholicacid,TUDCA
Description:
Molecular Formula: C26H45NO6S
Formula Weight: 499.7
Melting Point:
Solvent:
Purity (%): ≥ 98
Storage: Store at 2-8C, dry place. Avoid light.
Tauroursodeoxycholic acid (TUDCA) is an ambiphilic bile acid. It is the taurine conjugate form of ursodeoxycholic acid (UDCA). Humans are found to have trace amounts of TUDCA. However, bears contain large amounts of TUDCA in their bile; UDCA and conjugates comprise about 47% of the bile in American black bears and up to 76% in Asiatic bears.TUDCA has been used in ancient Asian pharmacopoeias for its supposed beneficial effects. UDCA is produced in several countries for the treatment of gallstones and liver cirrhosis. It is not approved by the Food and Drug Administration, in the U.S. while UDCA is approved in the United States for the treatment of primary biliary cirrhosis Ongoing research is finding TUDCA has diminishing apoptotic effects, helping with cardiac function, Huntington's disease, Parkinson's Disease, and stroke Recently, TUDCA has been found to have protective effects in the eye, especially concerning retinal degenerative disorders.
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2016年2月1日星期一
Mystery PI3K between cancer cells
PI3K (phosphatidylinositol three kinase) is a cell signaling molecule, the molecule primarily involved in a series of female cancers occur, such as breast cancer, ovarian cancer and endometrial cancer; recently published in the journal Cell One study papers, from Beth - Israel - Deaconess medical Center researchers (Beth Israel Deaconess medical Center) reveals the PI3K new role in the process of glycolysis, glycolysis is a special kind of metabolic processes, which can be facilitated by the generation of biomass energy and cancer cells continue to grow, studies confirm the importance of sugars on cancer cells to survive and provide new information for the development of PI3K inhibitor drugs as a targeted cancer therapy offers hope.
Researcher Dr. Gerburg Wulf representation, PI3K is a cancer cell can be integrated architecture and its main regulators of metabolic processes, and how to coordinate between sugar molecules and broken cell structure is still a puzzle. In normal cells, the external signal activates the cytoskeleton, and the cytoskeleton is not fixed, it is dynamically assembled from the fiber bundle, and continue to flip through, broken ATP molecule to maintain cell shape, the researchers found that when PI3K is activate and intensify ATP broken in a cancer cell occurs, actin fibers and spin-off will release called aldolase enzymes.
PI3K was first discovered 20 years ago, when its function under normal circumstances PI3K pathway would regulate critical cellular functions, including cell growth, motility, proliferation and differentiation, but excessive activation of the PI3K signaling pathway will lead to breast cancer, ovarian cancer and other female cancers occur, based on the above findings, PI3K inhibitor development may be the only way to develop cancer individualized therapy. Researchers believe that suppression of glucose PI3K crushing will have a profound inhibitory effect, which is very important for cancer, because cancer cells depends on the carbohydrate metabolism update from me, it will not only produce energy but also produce Biomass.
Researcher Dr. Gerburg Wulf representation, PI3K is a cancer cell can be integrated architecture and its main regulators of metabolic processes, and how to coordinate between sugar molecules and broken cell structure is still a puzzle. In normal cells, the external signal activates the cytoskeleton, and the cytoskeleton is not fixed, it is dynamically assembled from the fiber bundle, and continue to flip through, broken ATP molecule to maintain cell shape, the researchers found that when PI3K is activate and intensify ATP broken in a cancer cell occurs, actin fibers and spin-off will release called aldolase enzymes.
PI3K was first discovered 20 years ago, when its function under normal circumstances PI3K pathway would regulate critical cellular functions, including cell growth, motility, proliferation and differentiation, but excessive activation of the PI3K signaling pathway will lead to breast cancer, ovarian cancer and other female cancers occur, based on the above findings, PI3K inhibitor development may be the only way to develop cancer individualized therapy. Researchers believe that suppression of glucose PI3K crushing will have a profound inhibitory effect, which is very important for cancer, because cancer cells depends on the carbohydrate metabolism update from me, it will not only produce energy but also produce Biomass.
Fenazox price
Product name:Fenazox
CAS: 61618-27-7
Molecular Formula: 61618-27-7
Molecular Weight: 295.27
Product description:Used in the treatment of chronic rheumatoid arthritis, deformation joint, wrist of low back pain, periarthritis of shoulder, neck shoulder syndrome and after surgery, trauma and inflammation after tooth extraction, after the pain. Is also a potent platelet aggregation inhibitors.
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HGH 191AA
A long-acting synthetic activity of somatostatin-like cyclic peptide. Pasireotide allows a wide variety of somatostatin receptors that have a much higher binding affinity for the somatostatin receptors 1, 3 and 5 as octreotide in vitro and a comparable binding affinity for the somatostatin receptor 2. this method is more effective than in the inhibition of somatostatin, the release of human growth hormone (HGH), glucagon and insulin.
Art is a gentle pill
B dancers and Parkinson's patients, these two terms at the same time never seems to set in one person. Worldwide, 10 million people suffer from Parkinson's, a progressive movement disorder that disease mostly occurs in older people, stiff limbs, tremors from time to time and bad sense of balance allows us to have an initial understanding of Parkinson's patients .
But in the past 15 years or so, they are among the thousands of people participated in the program belongs to Dance for PD part of dance classes. Dance for PD was started in Brooklyn, now throughout the United States and around the world. Also, because the dance may ease Parkinson's symptoms, the course also attracted scientists' attention and interest.
This has been around for 5 years, the project is located in Venice, Los Angeles, California, where Los Angeles is an important cultural center, with canals, beaches and street artists known. On a normal afternoon, nearly 24 "Broadway Baby" trying to imitate accompanied by music teacher Linda Berghoff dance movements. These students are Parkinson's patients and their spouses or caregivers.
Each of them sitting there, the upper body erect, arms extended, with the music doing rallying movement. This is not a small challenge for Parkinson's patients, while waving their arms to take the time to 1-2, when the third shot with the other side. Berghoff has been with everyone shouting encouragement. She was very thin, healthy, looks than her actual age of 65 years to be smaller. Although she has never been a professional dancer, but dancing throughout her entire life, even 10 years ago, she was diagnosed with Parkinson's disease.
"When I know I got sick, I might never dance again the idea scared me," she said, "I feel my favorites are deprived of the same." The same diagnosis hit Laura Karlin, the Berghoff as a her second mother's friend. Karlin can support Berghoff trying to find things. She asked Berghoff, "you want to practice yoga together? Do you want to dance with me? Do you want to do with a dance class?"
But in the past 15 years or so, they are among the thousands of people participated in the program belongs to Dance for PD part of dance classes. Dance for PD was started in Brooklyn, now throughout the United States and around the world. Also, because the dance may ease Parkinson's symptoms, the course also attracted scientists' attention and interest.
This has been around for 5 years, the project is located in Venice, Los Angeles, California, where Los Angeles is an important cultural center, with canals, beaches and street artists known. On a normal afternoon, nearly 24 "Broadway Baby" trying to imitate accompanied by music teacher Linda Berghoff dance movements. These students are Parkinson's patients and their spouses or caregivers.
Each of them sitting there, the upper body erect, arms extended, with the music doing rallying movement. This is not a small challenge for Parkinson's patients, while waving their arms to take the time to 1-2, when the third shot with the other side. Berghoff has been with everyone shouting encouragement. She was very thin, healthy, looks than her actual age of 65 years to be smaller. Although she has never been a professional dancer, but dancing throughout her entire life, even 10 years ago, she was diagnosed with Parkinson's disease.
"When I know I got sick, I might never dance again the idea scared me," she said, "I feel my favorites are deprived of the same." The same diagnosis hit Laura Karlin, the Berghoff as a her second mother's friend. Karlin can support Berghoff trying to find things. She asked Berghoff, "you want to practice yoga together? Do you want to dance with me? Do you want to do with a dance class?"
Anhydrous aluminium silicate
Product name:Anhydrous aluminium silicate
Description:Anhydrous aluminium silicate is loose white powder.Moisture:0.03%.PH Value:6.5~7.5.Oil absorption value:60±5.In the world coatings industry has been widely used.
From:http://www.chemicalspharm.com/New-Products/Anhydrous-aluminium-silicate/
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