Monoammonium Glycyrrhizinate S

Ammonium glycyrrhizinate nanoparticles loaded chitosan were prepared by ionic gelation of chitosan with tripolyphosphate anions (TPP). The particle size and zeta potential of the nanoparticles were determined by each dynamic light scattering (DLS) and zeta potential analyzer. Effects, including the molecular weight of chitosan, concentration of chitosan, concentration of ammonium glycyrrhizinate and polyethylene glycol (PEG) have studied the physicochemical properties of the nanoparticles. These nanoparticles have efficiency loading of ammonium. The encapsulation efficiency decreased with increasing concentration of ammonium glycyrrhizinate and the concentration of chitosan. The introduction of PEG can significantly reduce the positive charge of the particle surface. These studies showed that chitosan may TPP complex stable cationic nanoparticles to read the form of ammonium loading.

Glut5

Fructose is now an important part of human nutrition, increasing attention is focused on GLUT5 fructose transporter. In this article, we describe the regulation of GLUT5 not only in the intestines and testes, where it was discovered for the first time, but also in the kidney, skeletal muscle, adipose tissue and the brain, where cell types increasingly found GLUT5. The levels of expression of glut5 and fructose uptake rates were also significantly affected by diabetes, hypertension, obesity and inflammation and appear to be induced in the development of cancer, in particular in the mammary glands. We end up research centers focus on providing the information required by the role of GLUT5 during normal development, metabolic disorders and cancer, to better understand.
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Thrombopoietin price

Product Name: thrombopoietin

Type: Other biological products

Product Description:
Thrombopoietin, also referred to as TPO is a glycoprotein hormone, mainly by the liver and the kidneys that regulates the production of platelets by the bone marrow. It stimulates the production and differentiation of megakaryocytes, cells from the bone marrow, which fragment in a large number of platelets.
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LCC9 Abstract

acquired resistance to anti-estrogen is a major problem in the clinical treatment of endocrine reaction initially metastatic breast cancer. We have already shown that estrogen and MCF7 independent -responsive / LCC1 human breast cancer cells to resist triphenylethylene selected tamoxifen, a variant (MCF7 / LCC2) produce, sensitivity steroidal antiestrogen ICI 182,780 (N. Brunner et al reserves., Cancer Res, 53 :. 3229-3232, 1993). We now have the progressive vitro selection from 10:00 to 1 microM ICI 182,780 against MCF7 / LCC1 and gets a variant ICI 182,780 permanent resistant MCF7 / designated LCC9 applied. Unlike MCF7 / MCF7 4-hydroxy-LCC2 selected cells / LCC9 to present a complete cross-resistance to tamoxifen, has been exposed, despite never to this drug. Tamoxifen cross resistance born at the beginning of the selection, the following selection against only 0.1 nM ICI 182,780 clear. Although limited resistance against ICI 182,780 182,780 also observed resistance was not recognized until the selection pressure to 100 nM ICI increased 182,780 full HERE. Cross-resistance to tamoxifen remained during this additional selection. Despite their cross antiestrogen resistance, the MCF7 / LCC9 a level of expression of estrogen receptor retain comparable to that of their parent cells / LCC1 of MCF7. Whereas cells / LCC1 of MCF7 retain estrogen-inducible expression of progesterone receptors, show MCF7 / LCC9 of expression upregulated in both the progesterone receptor mRNA and protein unresponsive estrogen. independent estrogen and -responsive components MCF7 / LCC9 phenotype are obviously in vivo. These cells slowly form tumors in nude athymic mice ovariectomized but develop mitogenic response of estrogen supplements. The in vivo growth of MCF7 tumors / of LCC9 not affected by treatment with ICI 182,780. Although there is evidence of tamoxifen stimulation of tumor growth, this did not reach statistical significance. If this cross-resistance pattern occurs in some patients with breast cancer, antiestrogens triphenylethylene as first-line treatment with a cross-over administration of compounds to a repeat steroid may be advantageous.

Fe(CO)5 iron pentacarbonyl

Product name: Fe (CO) 5 iron pentacarbonyl
Product Description: Fe (CO) 5, the compounds of Co and Fe, the equation for the chemical reaction: 5CO + Fe → Fe (CO) 5
Physical properties: Under normal atmospheric, it was amber liquid, the density is 1.453 g / cm3 (20.0 ℃). Fe (CO) 5, the melting point is about -20.3 ℃, the point 103.6 ℃, the critical temperature of 286 ℃ boiling. The low temperature to the critical temperature, with the rise in temperature, it is easy to break Fe and Co.
Chemical properties:
1, Fe (CO) 5 is completely dissolved in benzine, benzene, tetrahydronaphthalene, benzaldehyde, acetone, bromination of benzene, benzene and the other solution dichloride.
2, of-15 ℃, steam carbonyl content mixed with the combustion air necessarily create; Less than 34 ℃ temperature, it may be a spontaneous combustion in air.
3, Fe (CO) 5 is very agile and easy to hydrogenated carbonyl content H2Fe (CO) 4 and a metal salt Na2Fe (CO) 4, Fe content halogenating carbonyl (CO) 4I2, and Gerber acyl Fe carbonyl content (CO) 2 form (NO) 2, carbonyl fullerenes [C5H5Fe (CO) 2] and other compounds.
4, Fe (CO) 5 photochemical performance is lively, under the light, Fe (CO) 5 is easy to resolve.
5 depending on the critical temperature of Fe (CO) 5, under normal atmospheric pressure and more than 286 ℃ for thermal decomposition is the most important application of Fe (CO) 5, and is the easiest way industrialization carbonyl .
Application: Pyrolysis micro powder / nano level carbonyl iron, nano iron oxide powder is, magnetic film at the nanometer scale, fiber, nine carbonyl two iron, gasoline, flame retardants, catalysts of anti-explosion agent, CEO of surface film coating, lithography mask iron, antibiotics etc.
Notes: Fe (CO) 5 is tasteless, toxic, flammable, explosive brown liquid, in transportation and storage, we should pay attention to:
1.iron pentacarbonyl be provided in anaerobic jars under sealed metal pressure in air.
2. iron pentacarbonyl should be stored in a cool, well-ventilated place, avoid direct sunlight, away from fire, heat source.
3. gentle with her collision prohibited.

LIN28A Antibody (N-term)

Product Name: LIN28A Antibody (N-term)

Other Names: Lin-28 homolog A; Zinc finger CCHC domain-containing protein 1; LIN28; CSDD1; LIN28A; ZCCHC1.

Target/Specificity: This LIN28A rabbit antibody immunized with a KLH conjugate produced synthetic peptide is between 17 ~ 47 amino acids of the N-terminal region of human LIN28A.

Application Notes: 
The suggested dilution is: 
ELISA        1:1,000 
Western blotting      1:100~500 
Immunohistochemistry        1:10~50   
   
Format:supplied to the in PBS purified polyclonal antibody containing 0.09% (w / v) sodium azide. This antibody was purified by protein A column followed by purification by affinity peptide.

Storage: Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Precautions: LIN28A Antibody (N-term) is for re

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Betamethasone

A glucocorticoid orally, parenterally, applied by local injection, inhalation, or topically in the treatment of various diseases, including corticosteroids are called. His lack of mineralocorticoid is betamethasone particularly suitable for cerebral edema and congenital adrenal hyperplasia Treaty.