2016年2月23日星期二
Glut5
Fructose is now an important part of human nutrition, increasing attention is focused on GLUT5 fructose transporter. In this article, we describe the regulation of GLUT5 not only in the intestines and testes, where it was discovered for the first time, but also in the kidney, skeletal muscle, adipose tissue and the brain, where cell types increasingly found GLUT5. The levels of expression of glut5 and fructose uptake rates were also significantly affected by diabetes, hypertension, obesity and inflammation and appear to be induced in the development of cancer, in particular in the mammary glands. We end up research centers focus on providing the information required by the role of GLUT5 during normal development, metabolic disorders and cancer, to better understand.
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