What is Ofloxacin Hydrochloride

Ofloxacin and ciprofloxacin are fluoroquinolones with similar characteristics. However, large differences in antimicrobial activity, a clinical benefit can be observed, and pharmacokinetics and interaction profiles. Ofloxacin is active in the urethral chlamydia; effectively eradicate lung infections and staph infections, and Streptococcus pneumoniae. Furthermore, ofloxacin did not change significantly the concentration of theophylline. Ciprofloxacin has better activity against Gram-negative bacilli, a benefit that will be canceled by ofloxacin serum half-life and longer levels. Therefore, when both drugs are effective as the treatment of infections by Gram-negative organisms, ofloxacin is also useful in the treatment of: 1) infections, wherein the two aerobic gram-negative rods and staphylococci or S. pneumoniae have been documented or suspected 2) urethritis, particularly in C. trachomatis is 3) infections or suspected in patients who received simultaneously theophylline.