2015年12月10日星期四
Roflumilast for sale
Product name:Roflumilast
CAS:162401-32-3
Molecular Formula:C17H14Cl2F2N2O3
Formula Weight:403.21
Description:
Roflumilast (expected trade name Daxas) is a drug which acts as a selective, long-acting inhibitor of the enzyme PDE-4. It has antiinflammatory effects and is under development as an orally administered drug for the treatment of inflammatory conditions of the lungs such as asthma, chronic obstructive pulmonary disease (COPD) and emphysema.While roflumilast was found to be effective in clinical trials, it produced several dose-limiting side effects including nausea, diarrhoea and headache, and development is continuing in an attempt to minimise the incidence of side effects while retaining clinical efficacy.
In June 2010 it was approved in the EU for severe COPD associated with chronic bronchitis.
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