2015年12月29日星期二

Enhance memory study found that a protein

Increase brain levels of a specific DNA recombinase can significantly improve their cognitive abilities. This finding is subject neuroscience research center headed by Prof. Hilmar Bading of Heidelberg University Cross. Mice show, Dnmt3a2 protein can improve memory. Because this protein will affect the fear of memory and the ability to remove such bad memories, researchers hope these findings can be used to develop new treatments for traumatic neurosis and other forms of anxiety. The results of this study are published in the "Molecular Psychiatry" magazine.

In an earlier study, the scientists found that low levels of Dnmt3a2 protein in the brain of aging mice. When older animals were injected with the virus produces this protein, that will increase their ability to remember. "We have now found that increasing Dnmt3a2 level in the brain of young mice can improve their cognitive abilities." Bading professor explained. In many different long-term memory tests, including typical Pavlovian conditioning experiment, the scientists were able to prove that there is more Dnmt3a2 mice behaved better.

Dnmt3a2 is an epigenetic regulator, it can be chemically modify the genetic material DNA. The result is the production of a specific protein changes in velocity. Activation of gene transcription of genetic information can be transferred to RNA, followed by the synthesis of new proteins, play an important role in memory consolidation and disappearing. Heidelberg neuroscientists and therefore in a patient using allopathic methods are similar to "eliminate" the experiment. This therapy for the treatment of traumatic neurosis, aimed interrupt or even completely eliminate disturbing relevance. We found that the brain contains a high level of Dnmt3a2 mice can eliminate the pain associated with a particular region and stimulate greater role between. "Bading explained.

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