Zidovudine

Product Name: zidovudine
CAS: 30516-87-1
Molecule formula: C10H13N5O5
Formula Weight: 283.24
Description:
Zidovudine (INN) or azidothymidine used (AZT) (also called ZDV) is a nucleoside transcriptase inhibitor analogue reverse (INTI), a type of antiretroviral drugs to treat HIV / AIDS. It is an analog of thymidine.
AZT was the first treatment approved for HIV, under the name Retrovir and sold Retrovis. the use of AZT was a major breakthrough in the treatment of AIDS in the 1990s, which changed significantly during the disease and helped destroy the idea that HIV / AIDS was a death sentence immediate. AZT slowed considerably the spread of HIV, but they do not stop completely. This allows HIV over time become resistant AZT, and for this reason AZT is usually in conjunction with other NRTIs and antiviral drugs. In this form AZT is used as an ingredient in Combivir and Trizivir among others. Zidovudine is included in the "List of essential medicines" World Health Organization, a list of minimum medical needs for a basic health care system.