2016年1月20日星期三
Silicon metal 553, 441, 331, 2202 meaning for sale
Development of a simple and cost-effective strategy for the diagnosis and treatment of cancer with a single and minimum dosage by non-invasive strategies are very demanding. To make theranostics effective strategy is the only light photodynamic induced reactive and photothermal imaging capability with highly desirable to double modal. Here, a non-covalent simple approach was chosen to immobilize hydrophobic silicon naphthalocyanine bis (trihexyl the oxide) (SiNc4) of photosensitizer on the fluorescent graph (MFG) as a result of stacking of π-π MFG magnetic SiNc4 in water and acted as nano Theragnostics. Taking advantage of the wide absorption in the near infrared (600-1200 nm) graph photosensitizer each wavelength in this range, the individual light-induced phototherapy facilitate. Spectra of phosphorescence, singlet oxygen sensor (green) SOSG experiences and 1,3-diphenyl isobenzofuran quenching studies confirm the production of singlet (1) O2 irradiation. Confocal micrographs show successful internalisation of MFG-SiNc4 in HeLa cells; while the magnetic resonance images in T2 MFG show a darkening effect of the significant concentration-dependent. Photodynamic / photothermal In in vitro treatment studies on HeLa cells showed that the effectiveness of murder MFG-SiNc4 with a single light source ~ 97.9%, probably due to the combined effects of the production of species reactive oxygen, local heating, and induction of apoptosis. MFG SiNc4 developed can be used as a potential for a double Theranostic Nano modal imaging and therapy of cancer cells with single light source for the effective treatment time and cost with a minimal dose treatment.
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