Two simple, accurate, reproducible and economical UV spectrophotometry and HPLC method for the simultaneous determination of two components itopride hydrochloride drug mixture and rabeprazole developed from combined as capsule assay. Originally developed method involves the formation and solution of systems of equations at 265.2 nm and 290.8 nm of two wavelengths. Second method is based on two calculating the wavelength was selected wavelengths for estimating itopride hydrochloride 278.0 nm and 298.8 nm and 253.6 nm rabeprazole sodium and 275.2 nm . developed HPLC method is a method in -chromatographisches reverse phase using a Phenomenex C18 column and acetonitrile: phosphate buffer (35:65 v / v), pH 7.0 as mobile phase. All methods developed obey Beer's law used in the concentration range for each method. Assay results have been validated by statistical studies and recovery.
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