2016年3月9日星期三
What is HeLa S3
In contrast to previous reports, this study of HeLa, HeLa S3 cells, and Hep-2 revealed that karyotypes of each cell line are characterized by a composition of uniform chromosomal marker and a constant number of copies for both normal chromosomes and markers. Based on these fingerprints and chromosomal analysis of metaphases 50 modal karyotype is defined each cell line. Each modal karyotype was the composite of the content previously reported karyotypes of the same cell line, and in general, the former is the same or a higher number of chromosome copies that he had. These modal karyotype can be used as a standard to identify and further individualize both the cell line and a subline in this cell line. We also found that many cells of each cell line have the same karyotype. Digital data parts are compiled in a table format by which the amount of difference between chromosomes crops can be easily compared. Also coming soon are chromosomal changes discussed characteristics can help distinguish clonal derivatives derived from cross-contamination of cell lines lines.
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