If only to reduce the body's thermostat a few weeks the state will be able to play a slimming effect, sound is not that great? Researchers have recently discovered that this is indeed a viable option, at least in mice can produce short-term results. The reason, perhaps the bacteria in their intestinal trouble.
Gastroenterology experts from the University of Minnesota's Alexander Khoruts said the study found a new microbial community on physiological characteristics of the host. Such research may eventually help us find the key substance secreted by microorganisms to help control people's weight.
Gut microbes refers intestinal parasites in the host bacteria and other life forms. A series of studies have shown that gut microbes involved in a number of physiological activities of the body, affecting a large range. In order to further understanding, from the University of Geneva in Switzerland physiologist Mirko Trajkovski, who for the relationship between the gut microbiota and metabolism study conducted in-depth. Previous studies have told them some gut microbes once missing, the body temperature of the environment will no longer be able to maintain body temperature. He therefore considered the gut microbes and the body temperature control, and there may be some link between body weight.
In order to clarify this issue, they analyzed the types of experimental mice intestinal parasitic microorganisms. These mice optimum temperature is 21 degrees life, the temperature was lowered to 6-11 degrees, for a period of one month (to be placed in the wild mice similar living environment). During the experiment the researchers continuously measures body temperature of mice, sampling their droppings, and wickedness of some other metabolic indicators, such as insulin intake and fat accumulation of species.
Under normal circumstances, the body weight of mice with age becomes larger increase in body temperature constant. Test, low temperature processing can instantly reduce the body temperature, so the mice had to burn fat for energy. While blood glucose levels will be reduced, increasing the sensitivity of mice to insulin. In addition, they are also types of intestinal microbial change significantly. A class called Akkermansia muciniphila bacteria (often associated with obesity and diabetes are closely related) disappear. Once this happens, the mouse will no longer be able to skillfully digest food to produce energy. The author's research results published in the "cell" the latest issue of the magazine.
However, a week after treatment, weight loss trend began to stop, intestinal ability to absorb energy and begin to recover. Anatomy of the test results showed that the mice increased intestinal surface area, thus the efficiency of digestion of food increased.
In order to examine whether changes in microbial species produce these physiological changes. Researchers microbes living cryogenic mice removed and transferred to a sterile normal mice treated intestine. The results show that these mice with previous similar weight loss phenomenon.
没有评论:
发表评论