Advances in genomics and metabolic clinical medicine

The human body is a complex system that exists in this system of biological molecules interrelated, interdependent. In recent years, people have realized the complexity of the overall complexity of the interaction of genetic makeup and environmental factors as well as between biology, but these interactions can not be understood merely from genomics, proteomics or transcriptomics level to reveal . Attention to the dynamic changes in the relationship between the biological and molecular pathways and network systems biology (systems biology) or Global Systems Biology , through the study of DNA, the interaction between RNA, proteins and metabolites between integration various biological information from a global reflection of genetic background and the environment on the role and impact of individual organisms. Metabolomics (metabolomics or metabonomics) is an important component of systems biology, is the latest of the "omics, genomics," since 1999, proposed by the rapid development Nicholson and become hotspot in recent years, it has been widely used disease early diagnosis, drug development, toxicity evaluation, environmental assessment, physiology, functional genomics, personalized medicine, nutrition and other fields of science. Life activities take place mostly within the cell metabolic level, so Metabolomics is considered the ultimate direction of "omics" research. It is believed that the genome, proteome and metabolome is the study of life processes on different levels and levels of science and technology platform, and metabolomics is an extension of genomics and proteomics. As Billy David said: "Genomics and Proteomics to tell you what could happen, and metabolomics will tell you what has happened."