Testosterone

17-beta hydroxysteroid dehydrogenase-3 deficiency is a condition that affects male sexual development. People with this condition are genetically male with an X and a Y chromosome in each cell and they have male gonads (testes). Your body does not produce enough of the male sex hormone testosterone. Testosterone has a crucial role in male sexual development, and a lack of this hormone interferes with the formation of the external sex organs before birth. Most people with 17-beta hydroxysteroid dehydrogenase 3 deficiency are born with genitalia that appear woman. In some cases, the external genitalia not clearly look to clear male or female (sometimes called ambiguous genitalia). Yet other children affected have genitals that appear male-dominated, often with abnormally small penis (micropenis) or urethral opening on the underside of the penis (hypospadias). During puberty, men develop the disease of secondary sexual characteristics such as increased muscle mass, deepening of the voice, and the male body hair development. The penis and scrotum (the bag of skin that holds the testicles) grow up in this period. In addition to these changes typical of adolescent boys, some breast enlargement men affected (gynecomastia) can also occur. Men with this condition are generally not able to have children (infertile). Children who often grew up with 17-beta hydroxysteroid dehydrogenase 3 deficiency than girls. assume about half of them a male role in adolescence or adulthood