Stem cell therapy to humans by a cat

When the kitten Bob came to the University of California at Davis veterinary hospital, it has exhausted its nine lives; inflammation of the mouth due to the torture, Bob has been pulled all the teeth and trying to name this cat class chronic gingivostomatitis (FCGS) the fight against the disease, and finally Bob into a small clinical trial to accept a new type of stem cell therapy for treatment. Bob and other small cat as a very fortunate to enter into this clinical trial, the test was a success, Bob gained a new life.

The results of this study the researchers published in the journal Stem Cells Translational Medicine; articles first time, researchers using stem cell therapy successful and effective in the treatment of feline chronic gingivostomatitis disease; Arzi when researchers saw a lot due to treatment chronic gingivostomatitis lost all teeth cat, he opened a special treat feline disease clinical trials; feline chronic gingivostomatitis is a difficult to treat disease, researchers often see some of the cats the traditional therapy and nothing happens, so they decided to use stem cell therapy to try; first they use a cat body's own fat-derived stem cells, stem cell processing and characterizing followed then these treated stem cells cats intravenous injection to reduce the body's inflammatory cat show, and promote tissue regeneration; researchers also identified a useful biomarker, which can help determine whether the cat will react to stem cell therapy.

Arzi said, the first time we use this new technology to test mammal as an animal disease, feline chronic gingivostomatitis disease might be able to, as a new model to help develop effective treatment of human chronic inflammatory diseases of the oral cavity new therapies.

Researchers Nasim Fazel previous relevant studies organization feline chronic gingivostomatitis chronic stomatitis and human diseases and pathology characteristic of inflammatory markers in the blood. Oral lichen planus is a similar feline chronic gingivostomatitis T cell-mediated chronic inflammatory mucosal diseases, Fazel said we are pleased that the disease has made a breakthrough, because the performance of cats with the disease oral lichen planus human pathology is very similar, based on the above research, the current researchers have submitted an application to establish human clinical trials, between the use of mesenchymal stem cell therapy to treat human OLP, believed by researchers late tireless efforts of their research in this field will make new research results.