2016年2月16日星期二

Dutasteride


A synthetic connection 4-asteroid. Dutasteride competitive and specific form of isoenzymes 1 and 2 of the 5-alpha-reductase enzyme complex stable, and by inhibiting the conversion of testosterone to 5 alpha-dihydrotestosterone (DHT); The reduction in DHT activity can reduce prostate enlargement or prevented. The isoenzyme 2-5-alpha-reductase type is primarily in reproductive tissues, while the type 1 isozyme is also active in the skin and liver.

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